Hacettepe University Faculty of Medicine, Department of Chest Diseases, Ankara, Turkey.
Tuberk Toraks. 2021 Jun;69(2):144-152. doi: 10.5578/tt.20219803.
Oxygen desaturation is a significant event during bronchoscopy. In this study, it was aimed to identify factors related to oxygen desaturation during flexible bronchoscopy (FB) and Endobronchial ultrasound (EBUS).
From 16 April 2019 to 14 February 2020, 196 consecutive patients (146 FB and 50 EBUS) undergoing bronchoscopy were evaluated retrospectively. The patients' oxygen saturations were monitored on admission and during the procedure by finger pulse oximetry. Desaturation was defined as saturation below 90%. Demographic characteristics, comorbidities, types of interventions, vitals before and during the procedure, amount of saturation decline, and sedative agents used were recorded. The data obtained were compared between the desaturated and non-desaturated groups in both FB and EBUS. We evaluated the risk factors for desaturation during bronchoscopic procedures.
The mean age of those who underwent FB was higher (62 [52-68] years vs. 55 [44-65] years, p= 0.05), and males were more frequent (54%, vs 19.2%, p<0.001) in the desaturated group. In FB, short lavage was more frequent in the non-desaturated group (28.8% vs. 9.5%, p<0.001). In EBUS, hypertension, diabetes mellitus and thyroid diseases were higher, and duration of procedure was longer (p= 0.02, p= 0.04, p= 0.01 and p<0.001 and p= 0.01, respectively), and SpO2 decline during procedures was higher (11% vs. 1% in FB, 18% vs. 3% in EBUS, p<0.001, each) in the desaturated group.
This study suggested that baseline SpO2 and SpO2 decline during procedures as well as sex, hypertension, and concomitant endocrine - metabolic diseases, duration of procedure were factors associated with desaturation in patients who had undergone FB and EBUS.
氧饱和度降低是支气管镜检查中的一个重要事件。本研究旨在确定与纤维支气管镜检查（FB）和支气管内超声（EBUS）期间氧饱和度降低相关的因素。
从 2019 年 4 月 16 日至 2020 年 2 月 14 日，回顾性评估了 196 例连续接受支气管镜检查的患者（146 例 FB 和 50 例 EBUS）。通过手指脉搏血氧仪监测患者入院时和检查过程中的血氧饱和度。氧饱和度降低定义为饱和度低于 90%。记录人口统计学特征、合并症、干预类型、检查前后生命体征、饱和度下降程度以及使用的镇静剂。比较了 FB 和 EBUS 中两组患者的血氧饱和度降低情况。我们评估了支气管镜检查过程中发生血氧饱和度降低的危险因素。
行 FB 的患者年龄较大（62[52-68]岁 vs. 55[44-65]岁，p=0.05），男性更为常见（54% vs. 19.2%，p<0.001）。在 FB 中，非血氧饱和度降低组中短冲洗更为常见（28.8% vs. 9.5%，p<0.001）。在 EBUS 中，高血压、糖尿病和甲状腺疾病更为常见，检查时间更长（p=0.02、p=0.04、p=0.01 和 p<0.001 和 p=0.01），并且检查过程中 SpO2 下降程度更高（FB 中 11% vs. 非血氧饱和度降低组 9.5%，EBUS 中 18% vs. 非血氧饱和度降低组 3%，p<0.001，分别）。
本研究表明，在接受 FB 和 EBUS 的患者中，基础 SpO2 和检查过程中 SpO2 下降程度以及性别、高血压和并存的内分泌代谢疾病、检查时间是与氧饱和度降低相关的因素。
