Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Brown School, Washington University in St. Louis, St. Louis, MO, USA.
J Natl Cancer Inst. 2021 Nov 29;113(12):1714-1722. doi: 10.1093/jnci/djab135.
Although Medicaid expansion is associated with decreased uninsured rates and earlier cancer diagnoses, no study has demonstrated an association between Medicaid expansion and cancer mortality. Our primary objective was to quantify the relationship between early Medicaid expansion and changes in cancer mortality rates.
We obtained county-level data from the National Center for Health Statistics for adults aged 20-64 years who died from cancer from 2007 to 2009 (preexpansion) and 2012 to 2016 (postexpansion). We compared changes in cancer mortality rates in early Medicaid expansion states (CA, CT, DC, MN, NJ, and WA) vs nonexpansion states through a difference-in-differences analysis using hierarchical Bayesian regression. An exploratory analysis of cancer mortality changes associated with the larger-scale 2014 Medicaid expansions was also performed.
In adjusted difference-in-differences analyses, we observed a statistically significant decrease of 3.07 (95% credible interval = 2.19 to 3.95) cancer deaths per 100 000 in early expansion vs nonexpansion states, which translates to an estimated decrease of 5276 cancer deaths in the early expansion states during the study period. Expansion-associated decreases in cancer mortality were observed for pancreatic cancer. Exploratory analyses of the 2014 Medicaid expansions showed a decrease in pancreatic cancer mortality (-0.18 deaths per 100 000, 95% confidence interval = -0.32 to -0.05) in states that expanded Medicaid by 2014 compared with nonexpansion states.
Early Medicaid expansion was associated with reduced cancer mortality rates, especially for pancreatic cancer, a cancer with short median survival where changes in prognosis would be most visible with limited follow-up.
尽管医疗补助计划的扩大与未参保率的降低和癌症早期诊断有关,但没有研究表明医疗补助计划的扩大与癌症死亡率之间存在关联。我们的主要目的是量化早期医疗补助计划扩大与癌症死亡率变化之间的关系。
我们从国家卫生统计中心获得了 2007 年至 2009 年(扩大前)和 2012 年至 2016 年(扩大后)死于癌症的 20-64 岁成年人的县一级数据。我们通过分层贝叶斯回归的差异分析比较了早期医疗补助计划扩大州(加利福尼亚州、康涅狄格州、哥伦比亚特区、明尼苏达州、新泽西州和华盛顿州)与非扩大州的癌症死亡率变化。还对与 2014 年更大规模的医疗补助扩大相关的癌症死亡率变化进行了探索性分析。
在调整后的差异分析中,我们观察到早期扩大组与非扩大组相比,每 10 万人中有 3.07 例(95%可信区间=2.19 至 3.95)癌症死亡人数显著下降,这意味着在研究期间,早期扩大组的癌症死亡人数估计减少了 5276 人。在早期扩张州,观察到与扩张相关的胰腺癌死亡率下降。对 2014 年医疗补助扩大的探索性分析显示,与非扩大州相比,2014 年扩大医疗补助的州胰腺癌死亡率下降了 0.18 人/每 10 万人(95%置信区间=-0.32 至-0.05)。
早期医疗补助计划的扩大与癌症死亡率的降低有关,特别是对于胰腺癌,这种癌症的中位生存期较短,在有限的随访中,预后的变化最为明显。