关于坏疽性脓皮病患者中成年人抑郁和焦虑的系统评价。

A Systematic Review of Depression and Anxiety in Adults with Pyoderma Gangrenosum.

机构信息

Meghan L. McPhie, PhD, is Medical Student, Queen's University, School of Medicine, Kingston, Ontario, Canada. At the University of Toronto, Ontario, Joshua Fletcher, MD, is Family Medicine Resident, Division of Dermatology; Myrela O. Machado, MD, is Clinical Fellow, Division of Dermatology; Andre F. Carvalho, MD, PhD, is Associate Professor of Psychiatry, Department of Psychiatry; and Vincent Piguet, MD, PhD, is Director, Division of Dermatology. Afsaneh Alavi, MD, MSc, is Associate Professor, Department of Dermatology, Mayo Clinic, Rochester, Minnesota. Acknowledgments: Dr Alavi has been consultant for AbbVie, BI, Janssen, InflaRx, Novartis, UCB, and an investigator for BI and Castle Creek. The authors have disclosed no financial relationships related to this article. Submitted August 13, 2020; accepted in revised form October 28, 2020.

出版信息

Adv Skin Wound Care. 2021 Aug 1;34(8):432-436. doi: 10.1097/01.ASW.0000755920.76330.21.

DOI:10.1097/01.ASW.0000755920.76330.21

PMID:34260421

Abstract

OBJECTIVE

To synthesize the available evidence on the prevalence and odds for anxiety and depression in adults with pyoderma gangrenosum (PG).

DATA SOURCES

Observational studies examining anxiety and depression in adults with PG were systematically searched using the MEDLINE, EMBASE, PsycINFO, and CINAHL databases from the inception of each database to March 11, 2020.

STUDY SELECTION

Two authors independently screened references based on predetermined eligibility criteria.

DATA EXTRACTION

Of the 244 articles identified, three met the eligibility criteria. Relevant data were extracted from included studies, and methodological quality was evaluated independently by two authors using the modified Newcastle-Ottawa Scale.

DATA SYNTHESIS

Three observational studies comprising 183 participants with PG met the inclusion criteria. Estimated rates of depression in adults with PG ranged from 10% to 23%. None of the studies measured rates of anxiety.

CONCLUSIONS

The current systematic review suggests that depression is a common psychological comorbidity in adults with PG. Additional research is required to further assess the psychological comorbidities in this population.

摘要