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新生儿社区获得性鸟氨酸罗伊氏菌败血症:病例报告及文献复习。

Neonatal Community-acquired Raoultella Ornithinolytica Septicemia: A Case Report and Review of the Literature.

机构信息

From the Division of Neonatology, Department of Pediatrics.

Department of Pediatrics, University of Health Sciences, Gulhane Medicine Faculty, Ankara, Turkey.

出版信息

Pediatr Infect Dis J. 2021 Oct 1;40(10):e370-e373. doi: 10.1097/INF.0000000000003197.

Abstract

Raoultella ornithinolytica is an opportunistic, aquaphilic and Gram-negative bacterium. Immune deficiency states and indwelling catheters provide a basis for most of the infections arising. R. ornithinolytica septicemia (ROS) is extremely rare in neonates but can be life threatening. Community-acquired ROS has not been described in neonates before. The diagnosis of neonatal septicemia is occasionally complicated by unusual clinical presentations. Pyloric stenosis is manifested by projectile, nonbilious vomiting and late findings, including weight loss, dehydration and electrolyte abnormalities beyond 4-6 weeks old. Community-acquired neonatal septicemia symptoms can sometimes be confused with symptoms of gastrointestinal obstructions in patients without risk factors for sepsis. Early diagnosis and appropriate antibiotics are essentials for a good prognosis in neonatal septicemia. Herein, we present a novel case of community-acquired ROS with an unusual presentation in a term infant and a review of the literature about ROS in the neonatal period.

摘要

鸟氨酸罗单胞菌是一种机会性、嗜水和革兰氏阴性细菌。免疫缺陷状态和留置导管为大多数感染提供了基础。鸟氨酸罗单胞菌败血症(ROS)在新生儿中极为罕见,但可能危及生命。以前没有描述过社区获得性 ROS 在新生儿中的情况。新生儿败血症的诊断偶尔会因不常见的临床表现而变得复杂。幽门狭窄的表现为喷射性、非胆汁性呕吐和晚期发现,包括体重减轻、脱水和电解质异常,超过 4-6 周大。没有脓毒症危险因素的患者,社区获得性新生儿败血症的症状有时可能与胃肠道梗阻的症状混淆。早期诊断和适当的抗生素是新生儿败血症良好预后的关键。在此,我们介绍了一例罕见的足月婴儿社区获得性 ROS 病例,并对新生儿期 ROS 的文献进行了回顾。

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