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[鞍上蛛网膜囊肿所致性早熟。6例分析]

[Precocious puberty caused by a suprasellar arachnoid cyst. Analysis of 6 cases].

作者信息

Brauner R, Pierre-Kahn A, Nemedy-Sandor E, Rappaport R, Hirsch J F

机构信息

Unité d'Endocrinologie Pédiatrique et Diabète, Hôpital des Enfants Malades, Paris.

出版信息

Arch Fr Pediatr. 1987 Aug-Sep;44(7):489-93.

PMID:3426371
Abstract

The authors report 6 cases (4 girls and 2 boys) with central precocious puberty associated with a suprasellar arachnoid cyst. Precocious puberty is rarely the presenting sign of arachnoid cysts. It was characterized by early onset, patent symptoms and frequent association (3 of 6 cases) with growth hormone deficiency. The latter represents a further risk of short stature. Evolution of precocious puberty varied from one case to another, without any relation with the quality of control of the arachnoid cyst and associated hydrocephalus. Half-yearly follow-up of height and bone age allowed for deciding a suppressive treatment of precocious puberty and a substitutive growth hormone therapy when needed.

摘要

作者报告了6例(4名女孩和2名男孩)伴有鞍上蛛网膜囊肿的中枢性性早熟病例。性早熟很少是蛛网膜囊肿的首发症状。其特点为起病早、症状典型,且常伴有生长激素缺乏(6例中有3例)。后者是身材矮小的又一风险因素。性早熟的病情发展因病例而异,与蛛网膜囊肿及相关脑积水的控制情况无关。通过每半年对身高和骨龄进行随访,可决定是否进行性早熟抑制治疗以及必要时的生长激素替代治疗。

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