• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

一名HIV阳性患者发生的累及肾脏的浆母细胞淋巴瘤：病例报告并文献复习

Plasmablastic Lymphoma Involving Kidney in an HIV Positive Patient: A Case Report with Review of the Literature.

作者信息

Sapkota Sulav, Priyadarshini Mona, Hazarika Diganta, Swamy Shivakumar, Naik Radheshyam

机构信息

Department of Hematology and Medical Oncology, HCG Hospital, Bengaluru, Karnataka, India.

Department of Gynae-Oncology, HCG Hospital, Bengaluru, Karnataka, India.

出版信息

Indian J Nephrol. 2021 Mar-Apr;31(2):176-178. doi: 10.4103/ijn.IJN_277_18. Epub 2021 Feb 8.

DOI:10.4103/ijn.IJN_277_18
PMID:34267442
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8240923/
Abstract

Plasmablastic lymphoma (PBL) is an aggressive lymphoma commonly associated with HIV infection. It most commonly presents in the oral cavity and rarely involves the kidney. Herein, we report a case of HIV positive male with renal involvement of PBL. The patient presented with unilateral severe hydronephrosis with unaltered renal functions. Despite aggressive management, there was an early relapse and the patient died within 2 years of the diagnosis. Despite the recent advances in the therapy of HIV-associated aggressive lymphomas, patients with PBL have a poor prognosis. Multimodal treatment with chemotherapy, newer targeted and biological agents, along with hematopoietic stem cell transplantation is essential for the treatment of PBL.

摘要

浆母细胞淋巴瘤（PBL）是一种侵袭性淋巴瘤，通常与HIV感染相关。它最常出现在口腔，很少累及肾脏。在此，我们报告一例HIV阳性男性发生肾脏受累的PBL病例。该患者表现为单侧严重肾积水，肾功能未改变。尽管进行了积极治疗，但仍早期复发，患者在诊断后2年内死亡。尽管在HIV相关侵袭性淋巴瘤的治疗方面有了最新进展，但PBL患者的预后仍然很差。采用化疗、新型靶向和生物制剂以及造血干细胞移植的多模式治疗对于PBL的治疗至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e377/8240923/954e74f62e7f/IJN-31-176-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e377/8240923/8cec77de824c/IJN-31-176-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e377/8240923/954e74f62e7f/IJN-31-176-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e377/8240923/8cec77de824c/IJN-31-176-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e377/8240923/954e74f62e7f/IJN-31-176-g002.jpg

相似文献

1
Plasmablastic Lymphoma Involving Kidney in an HIV Positive Patient: A Case Report with Review of the Literature.一名HIV阳性患者发生的累及肾脏的浆母细胞淋巴瘤：病例报告并文献复习
Indian J Nephrol. 2021 Mar-Apr;31(2):176-178. doi: 10.4103/ijn.IJN_277_18. Epub 2021 Feb 8.
2
Plasmablastic lymphoma of the retroperitoneum in an HIV- and HCV-positive patient: hard to diagnose and harder to treat.HIV 和 HCV 阳性患者腹膜后弥漫大 B 细胞淋巴瘤：诊断困难，治疗更难。
Med Oncol. 2012 Dec;29(5):3529-34. doi: 10.1007/s12032-012-0248-2. Epub 2012 May 6.
3
Plasmablastic lymphoma of the colon in HIV negative patient; a case report with literature review.HIV阴性患者的结肠浆母细胞淋巴瘤；一例报告并文献复习
Ann Med Surg (Lond). 2022 May 11;78:103750. doi: 10.1016/j.amsu.2022.103750. eCollection 2022 Jun.
4
Light chain cast nephropathy caused by plasmablastic lymphoma of the bladder.膀胱浆母细胞淋巴瘤引起的轻链管型肾病。
Clin Nephrol Case Stud. 2021 Jul 1;9:72-80. doi: 10.5414/CNCS110339. eCollection 2021.
5
Plasmablastic Lymphoma浆母细胞淋巴瘤
6
Extranodal Involvement of the Anorectal Region in an HIV-Positive Patient With Plasmablastic Lymphoma: A Case Report.一名HIV阳性的浆母细胞淋巴瘤患者的直肠肛门区域结外受累：病例报告
Cureus. 2022 Dec 30;14(12):e33151. doi: 10.7759/cureus.33151. eCollection 2022 Dec.
7
Lymphoid neoplasms of the oral cavity with plasmablastic morphology-a case series and review of the literature.具有浆母细胞形态的口腔淋巴样肿瘤——病例系列及文献复习
Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Dec;128(6):651-659. doi: 10.1016/j.oooo.2019.08.001. Epub 2019 Aug 19.
8
The biology and treatment of plasmablastic lymphoma.浆母细胞淋巴瘤的生物学特性与治疗。
Blood. 2015 Apr 9;125(15):2323-30. doi: 10.1182/blood-2014-10-567479. Epub 2015 Jan 30.
9
Plasmablastic lymphoma of the gastrointestinal tract: A rare entity with a dismal prognosis.胃肠道浆母细胞淋巴瘤：一种预后不佳的罕见实体。
Indian J Cancer. 2016 Oct-Dec;53(4):529-533. doi: 10.4103/0019-509X.204756.
10
Unexpected plasmablastic lymphoma in a young adult with unknown HIV infection: case report.一名不明HIV感染情况的年轻成人发生意外的浆母细胞淋巴瘤：病例报告
J Gastrointest Oncol. 2022 Jun;13(3):1467-1472. doi: 10.21037/jgo-21-779.

引用本文的文献

1
Acute kidney injury in an HIV patient with plasmablastic lymphoma - A double-edged sword.一名患有浆母细胞淋巴瘤的艾滋病患者出现急性肾损伤——一把双刃剑。
S Afr J Infect Dis. 2024 May 31;39(1):637. doi: 10.4102/sajid.v39i1.637. eCollection 2024.
2
Proliferative glomerulonephritis with monoclonal IgG Lambda deposits caused by plasmablastic lymphoma: a case report.由浆母细胞淋巴瘤引起的单克隆 IgG λ 沉积增殖性肾小球肾炎：一例报告。
BMC Nephrol. 2023 Oct 6;24(1):297. doi: 10.1186/s12882-023-03351-7.

本文引用的文献

1
Chimeric antigen receptor modified T cell therapy for B cell malignancies.嵌合抗原受体修饰的T细胞疗法治疗B细胞恶性肿瘤
Int J Hematol. 2014 Feb;99(2):132-40. doi: 10.1007/s12185-013-1490-x. Epub 2013 Dec 14.
2
Brentuximab vedotin demonstrates activity in a patient with plasmablastic lymphoma arising from a background of chronic lymphocytic leukemia.本妥昔单抗在一名源于慢性淋巴细胞白血病背景的浆母细胞淋巴瘤患者中显示出活性。
J Clin Oncol. 2013 Apr 20;31(12):e197-9. doi: 10.1200/JCO.2012.46.9593. Epub 2013 Mar 18.
3
Clinical and pathological differences between human immunodeficiency virus-positive and human immunodeficiency virus-negative patients with plasmablastic lymphoma.
人类免疫缺陷病毒阳性和人类免疫缺陷病毒阴性的浆母细胞淋巴瘤患者的临床和病理差异。
Leuk Lymphoma. 2010 Nov;51(11):2047-53. doi: 10.3109/10428194.2010.516040. Epub 2010 Oct 4.
4
Plasmablastic lymphoma in an immunocompetent patient.
J Clin Oncol. 2009 Sep 1;27(25):e78-81. doi: 10.1200/JCO.2009.22.2208. Epub 2009 Jul 6.
5
HIV-associated plasmablastic lymphoma: lessons learned from 112 published cases.与人类免疫缺陷病毒相关的浆母细胞淋巴瘤：从112例已发表病例中汲取的经验教训
Am J Hematol. 2008 Oct;83(10):804-9. doi: 10.1002/ajh.21250.
6
Plasmablastic lymphoma: a clinicopathologic correlation.浆母细胞淋巴瘤：临床病理相关性
Ann Diagn Pathol. 2006 Feb;10(1):8-12. doi: 10.1016/j.anndiagpath.2005.07.009.
7
Plasmablastic lymphomas and plasmablastic plasma cell myelomas have nearly identical immunophenotypic profiles.浆母细胞淋巴瘤和浆母细胞性浆细胞骨髓瘤具有几乎相同的免疫表型特征。
Mod Pathol. 2005 Jun;18(6):806-15. doi: 10.1038/modpathol.3800355.
8
Diffuse large B-cell lymphomas with plasmablastic differentiation represent a heterogeneous group of disease entities.伴有浆母细胞分化的弥漫性大B细胞淋巴瘤代表了一组异质性疾病实体。
Am J Surg Pathol. 2004 Jun;28(6):736-47. doi: 10.1097/01.pas.0000126781.87158.e3.
9
Plasmablastic lymphomas of the oral cavity: a new entity associated with the human immunodeficiency virus infection.口腔浆母细胞淋巴瘤：一种与人类免疫缺陷病毒感染相关的新实体。
Blood. 1997 Feb 15;89(4):1413-20.