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经蝶窦垂体手术的麻醉管理。

Anesthetic management during transsphenoidal pituitary surgery.

机构信息

Department of Anesthesiology, University of Virginia Health System, Charlottesville, Virginia, USA.

出版信息

Curr Opin Anaesthesiol. 2021 Oct 1;34(5):575-581. doi: 10.1097/ACO.0000000000001035.

Abstract

PURPOSE OF REVIEW

Pituitary adenoma resections comprise a large proportion of intracranial tumor surgeries. This patient population is medically and physiologically complex and requires careful perioperative planning and management on the part of the anesthesiologist. This review will summarize anesthetic considerations for pre, intra, and postoperative management of patients undergoing transsphenoidal pituitary surgery.

RECENT FINDINGS

An endoscopic approach is favored for patients undergoing transsphenoidal pituitary surgery. Hemodynamic monitoring is important to maintain cerebral perfusion and avoid risk of bleeding; however, 'controlled' hypotension may have adverse effects. Multimodal analgesia is effective for the management of postoperative pain and may reduce the risk of postoperative complications, including respiratory depression and postoperative nausea and vomiting.

SUMMARY

Transsphenoidal pituitary surgery is a preferred approach for the surgical management of nonfunctioning pituitary macroadenomas with symptoms of mass effect and functioning adenomas that cannot be otherwise managed medically. Understanding tumor pathologies and systemic effects are essential for preoperative planning and providing safe anesthetic care during the perioperative period.

摘要

目的综述

垂体腺瘤切除术是颅内肿瘤手术的重要组成部分。此类患者具有复杂的医学和生理学特征,需要麻醉医生在围手术期进行仔细的计划和管理。本文将总结经蝶窦垂体瘤手术患者的术前、术中和术后麻醉管理注意事项。

最新发现

经蝶窦垂体瘤手术采用内镜入路。血流动力学监测对维持脑灌注和避免出血风险很重要;然而,“控制性”低血压可能会产生不良影响。多模式镇痛可有效管理术后疼痛,并降低术后并发症的风险,包括呼吸抑制和术后恶心呕吐。

总结

经蝶窦垂体瘤手术是治疗有占位效应症状的无功能垂体大腺瘤和药物治疗无效的功能性腺瘤的首选方法。了解肿瘤病理和全身影响对于术前规划和提供围手术期安全的麻醉护理至关重要。

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