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一名患有肢端肥大症和多结节性甲状腺肿的患者接受内镜垂体手术时的麻醉挑战。

Anaesthetic challenges in a patient with acromegaly and multinodular goitre undergoing endoscopic pituitary surgery.

作者信息

Jamil Jabraan, Wan Hassan Wan Mohd Nazarudin, Ghani Ab Rahman, Yeap Tat Boon

机构信息

Anaesthesia and Intensive Care Unit, Hospital Queen Elizabeth, Kota Kinabalu, Malaysia.

Department of Anaesthesia and Intensive Care, Universiti Sains Malaysia, Kota Bharu, Malaysia.

出版信息

BMJ Case Rep. 2023 Feb 16;16(2):e250640. doi: 10.1136/bcr-2022-250640.

DOI:10.1136/bcr-2022-250640
PMID:36796871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9936288/
Abstract

Acromegaly is a progressive systemic disorder which is common among middle-aged women. A functioning growth hormone-secreting pituitary adenoma is the most common cause. Anaesthesia for pituitary surgery in patients with acromegaly is challenging. Rarely, these patients may develop thyroid lesions that may compromise the airway. We present the case of a young man with newly diagnosed acromegaly caused by a pituitary macroadenoma complicated by a large multinodular goitre. The aim of this report is to discuss the perianaesthetic approach in patients with acromegaly with a high risk of airway compromise undergoing pituitary surgery.

摘要

肢端肥大症是一种进行性全身性疾病,在中年女性中较为常见。功能性分泌生长激素的垂体腺瘤是最常见的病因。肢端肥大症患者垂体手术的麻醉具有挑战性。这些患者很少会出现可能危及气道的甲状腺病变。我们报告一例年轻男性,新诊断为垂体大腺瘤合并巨大结节性甲状腺肿所致的肢端肥大症。本报告的目的是讨论垂体手术气道受损风险高的肢端肥大症患者的围麻醉处理方法。

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本文引用的文献

1
Anesthetic management during transsphenoidal pituitary surgery.经蝶窦垂体手术的麻醉管理。
Curr Opin Anaesthesiol. 2021 Oct 1;34(5):575-581. doi: 10.1097/ACO.0000000000001035.
2
Global epidemiology of acromegaly: a systematic review and meta-analysis.肢端肥大症的全球流行病学:系统评价和荟萃分析。
Eur J Endocrinol. 2021 Jul 1;185(2):251-263. doi: 10.1530/EJE-21-0216.
3
Anaesthetic challenges for a patient with huge superior mediastinal mass in prone position.俯卧位下患有巨大上纵隔肿块患者的麻醉挑战。
BMJ Case Rep. 2021 Apr 9;14(4):e242118. doi: 10.1136/bcr-2021-242118.
4
Secrets to a successful awake fibreoptic intubation (AFOI) on a patient with odentogenous abscess.经口清醒纤维支气管镜插管(AFOI)成功的秘诀:针对伴有齿源性脓肿的患者。
BMJ Case Rep. 2021 Feb 19;14(2):e238600. doi: 10.1136/bcr-2020-238600.
5
Hyperprolactinemia in Acromegaly is Related to Prolactin Secretion by Somatolactotroph Tumours.肢端肥大症中的高催乳素血症与生长泌乳素细胞瘤分泌催乳素有关。
Horm Metab Res. 2020 Sep;52(9):647-653. doi: 10.1055/a-1207-1132. Epub 2020 Aug 5.
6
Assessment of Factors Associated With Internal Carotid Injury in Expanded Endoscopic Endonasal Skull Base Surgery.评估扩展经鼻内镜颅底手术中与颈内动脉损伤相关的因素。
JAMA Otolaryngol Head Neck Surg. 2020 Apr 1;146(4):364-372. doi: 10.1001/jamaoto.2019.4864.
7
MANAGEMENT OF ENDOCRINE DISEASE: Does gender matter in the management of acromegaly?内分泌疾病管理:在肢端肥大症的治疗中,性别是否重要?
Eur J Endocrinol. 2020 May;182(5):R67-R82. doi: 10.1530/EJE-19-1023.
8
Management of hormone-secreting pituitary adenomas.激素分泌性垂体腺瘤的管理
Neuro Oncol. 2017 Jun 1;19(6):762-773. doi: 10.1093/neuonc/now130.
9
Incidence and prevalence of acromegaly in a large US health plan database.美国一个大型健康计划数据库中肢端肥大症的发病率和患病率。
Pituitary. 2016 Jun;19(3):262-7. doi: 10.1007/s11102-015-0701-2.
10
Acromegaly: an endocrine society clinical practice guideline.肢端肥大症:内分泌学会临床实践指南。
J Clin Endocrinol Metab. 2014 Nov;99(11):3933-51. doi: 10.1210/jc.2014-2700. Epub 2014 Oct 30.