Kim K, DeMets D L
Division of Biostatistics, Dana-Farber Cancer Institute, Boston, Massachusetts 02115.
Biometrics. 1987 Dec;43(4):857-64.
Tsiatis, Rosner, and Mehta (1984, Biometrics 40, 797-803) proposed a procedure for constructing confidence intervals following group sequential tests of a normal mean. This method is first extended for group sequential tests for which the sample sizes between interim analyses are not identical or the times are not equally spaced. Then properties of this confidence interval estimation procedure are studied by simulation. The extension accommodates the flexible procedure by Lan and DeMets (1983, Biometrika 70, 659-663) for constructing discrete group sequential boundaries to form a structure for monitoring and estimation following a class of group sequential tests. Finally, it is demonstrated how to combine the procedures by Lan and DeMets and by Tsiatis, Rosner, and Mehta using a FORTRAN program.
齐亚蒂斯、罗斯纳和梅塔（1984年，《生物统计学》40卷，797 - 803页）提出了一种在对正态均值进行成组序贯检验后构建置信区间的方法。该方法首先扩展到用于成组序贯检验，其中各期中分析之间的样本量不相同或时间间隔不相等的情况。然后通过模拟研究此置信区间估计方法的性质。该扩展采用了兰和德梅茨（1983年，《生物统计学杂志》70卷，659 - 663页）的灵活方法来构建离散的成组序贯边界，以形成一类成组序贯检验后监测和估计的结构。最后，展示了如何使用一个FORTRAN程序将兰和德梅茨以及齐亚蒂斯、罗斯纳和梅塔的方法结合起来。
