Dermatology Clinic, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Dermatology Clinic, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Clin Dermatol. 2021 Mar-Apr;39(2):211-214. doi: 10.1016/j.clindermatol.2020.10.001. Epub 2020 Oct 16.
Acral persistent papular mucinosis (APPM) is a subtype of localized lichen myxedematosus (LM) characterized by the chronic development of white to skin-colored papules and limited to the extensor surfaces of the hands and distal part of forearms, in the absence of systemic or laboratory manifestations. There is a strong predominance in women. Histopathology shows focal accumulation of mucin in the upper portion of the dermis sparing the grenz zone. The etiology is unknown. It is a benign condition, although dynamic changes occur with the progressive development of additional lesions. No specific treatment is required, and patients should be reassured about the prognosis.
肢端持久性丘疹黏液病（APPM）是局限性黏液水肿性苔藓（LM）的一个亚型，其特征为白色至皮肤色丘疹的慢性发展，局限于手部的伸面和前臂的远端，无系统或实验室表现。女性发病有明显优势。组织病理学显示真皮上部局灶性黏蛋白积聚，避开了 Grenz 带。病因不明。这是一种良性疾病，尽管随着额外病变的逐渐发展会出现动态变化。无需特定治疗，应向患者保证预后良好。
