Takayama K, Takei M, Soejima T, Kumazawa J
Department of Urology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Br J Urol. 1987 Nov;60(5):428-32. doi: 10.1111/j.1464-410x.1987.tb05008.x.
Bladder pressure changes in the completely physiological state of dogs were recorded on voiding, coughing, defaecating, vomiting, etc, by a pressure transducer embedded in the submucosal layer of the anterior bladder wall. The static pressures in the standing and lying positions were almost the same at about 10 cm H2O and in the sitting position the pressures were about 30 cm H2O. The voiding pressure was recorded 28 times and ranged from 44 to 257 cm H2O (average 141). These data were higher than expected and we recommend further studies on the maximum voiding pressure. On voiding, various patterns of pressure curve were observed and in the monophasic pressure curve, which probably shows normal urination, there was a time difference between urine flow and voiding pressure curve. Our new method may be useful not only as a sensory device for neurogenic bladder patients but also as an experimental system to study the effect of drugs on autonomic nerves.
通过嵌入膀胱前壁黏膜下层的压力传感器,记录了狗在完全生理状态下排尿、咳嗽、排便、呕吐等过程中的膀胱压力变化。站立位和卧位的静态压力几乎相同,约为10 cmH₂O,坐位时压力约为30 cmH₂O。记录了28次排尿压力,范围为44至257 cmH₂O(平均141)。这些数据高于预期,我们建议对最大排尿压力进行进一步研究。排尿时,观察到各种压力曲线模式,在可能显示正常排尿的单相压力曲线中,尿流与排尿压力曲线之间存在时间差。我们的新方法不仅可能作为神经源性膀胱患者的传感装置有用,而且还可作为研究药物对自主神经作用的实验系统。