Ishihara A, Naitoh H, Katsuta S
College of General Education, University of Tokushima, Japan.
Brain Res. 1987 Dec 1;435(1-2):355-8. doi: 10.1016/0006-8993(87)91624-6.
The age-related changes in the total number of muscle fibers and motoneurons of the tibialis anterior and soleus muscles were studied using 10-, 65-, and 135-week-old rats. The number of fast twitch muscle fibers was decreased at age 65 weeks, while the numbers of slow twitch fibers and of alpha motoneurons were decreased only later, at age 135 weeks. Therefore, the degenerative process of muscle fibers differs with the fiber type.
利用10周龄、65周龄和135周龄的大鼠,研究了胫前肌和比目鱼肌中肌纤维和运动神经元总数的年龄相关变化。65周龄时快肌纤维数量减少,而慢肌纤维和α运动神经元数量仅在135周龄时才减少。因此,肌纤维的退化过程因纤维类型而异。