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2
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本文引用的文献

1
Evans syndrome in adults: an observational multicenter study.成人 Evans 综合征：一项观察性多中心研究。
Blood Adv. 2021 Dec 28;5(24):5468-5478. doi: 10.1182/bloodadvances.2021005610.
2
Transfusion replacement strategies in Jehovah's Witnesses and others who decline blood products.拒绝输用血液制品的耶和华见证人及其他人群的输血替代策略。
Clin Adv Hematol Oncol. 2020 Dec;18(12):826-836.
3
Evans' Syndrome: From Diagnosis to Treatment.伊文氏综合征：从诊断到治疗
J Clin Med. 2020 Nov 27;9(12):3851. doi: 10.3390/jcm9123851.
4
Evans syndrome in adults - incidence, prevalence, and survival in a nationwide cohort.成人 Evans 综合征：全国性队列研究中的发病率、患病率和生存率。
Am J Hematol. 2019 Oct;94(10):1081-1090. doi: 10.1002/ajh.25574. Epub 2019 Aug 9.
5
A Case of Pregnancy Complicated with Evans Syndrome with Sequential Development of Autoimmune Warm Antibody Hemolytic Anemia and Idiopathic Thrombocytopenic Purpura.一例妊娠合并Evans综合征，先后出现自身免疫性温抗体型溶血性贫血和特发性血小板减少性紫癜的病例。
Case Rep Obstet Gynecol. 2019 Jan 14;2019:2093612. doi: 10.1155/2019/2093612. eCollection 2019.
6
Evans syndrome: clinical perspectives, biological insights and treatment modalities.伊文斯综合征：临床观点、生物学见解及治疗方式
J Blood Med. 2018 Oct 10;9:171-184. doi: 10.2147/JBM.S176144. eCollection 2018.
7
Natural History, Pathogenesis, and Treatment of Evans Syndrome in Children.儿童Evans综合征的自然史、发病机制及治疗
J Pediatr Hematol Oncol. 2017 Aug;39(6):413-419. doi: 10.1097/MPH.0000000000000897.
8
How do we treat life-threatening anemia in a Jehovah's Witness patient?我们如何治疗耶和华见证会患者的危及生命的贫血？
Transfusion. 2014 Dec;54(12):3026-34. doi: 10.1111/trf.12888. Epub 2014 Oct 21.
9
Erythropoietin May Improve Anemia in Patients with Autoimmune Hemolytic Anemia Associated with Reticulocytopenia.促红细胞生成素可能改善伴有网织红细胞减少的自身免疫性溶血性贫血患者的贫血状况。
Transfus Med Hemother. 2012 Jun;39(3):221-223. doi: 10.1159/000339260. Epub 2012 May 15.
10
Management of Evans syndrome.伊文氏综合征的管理
Br J Haematol. 2006 Jan;132(2):125-37. doi: 10.1111/j.1365-2141.2005.05809.x.

一名耶和华见证会信徒患伊文氏综合征。

Evans Syndrome in a Jehovah's Witness.

作者信息

Leonhardt Lex P, Pervez Aamir, Calvo Alejandro

机构信息

Internal Medicine, Kettering Medical Center, Dayton, USA.

Hematology and Medical Oncology, Kettering Medical Center, Dayton, USA.

出版信息

Cureus. 2021 Jun 7;13(6):e15508. doi: 10.7759/cureus.15508. eCollection 2021 Jun.

DOI:10.7759/cureus.15508
PMID:34277157
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8269972/
Abstract

Evans syndrome (ES) is a rare hematologic disorder characterized by the development of autoimmune hemolytic anemia (AIHA), idiopathic thrombocytopenia, and occasionally immune-mediated neutropenia. Jehovah's Witnesses (JW) often decline blood product transfusion on the grounds of a scriptural stand based on biblical texts. The acute management of ES often consists of blood product transfusion in addition to high-dose steroids and intravenous immunoglobulin. We describe the case of a JW female presenting with new-onset, acutely worsening AIHA and thrombocytopenia with concern for hemodynamic compromise who was successfully treated with erythropoietin-stimulating agents, parenteral iron, folic acid, and high-dose steroids.

摘要

伊文斯综合征（ES）是一种罕见的血液系统疾病，其特征为自身免疫性溶血性贫血（AIHA）、特发性血小板减少症，偶尔还伴有免疫介导的中性粒细胞减少症。耶和华见证人（JW）常常基于圣经经文的教义立场而拒绝输血。ES的急性处理通常除了大剂量类固醇和静脉注射免疫球蛋白外，还包括输血。我们描述了一例JW女性患者的病例，该患者新发急性加重的AIHA和血小板减少症，伴有血流动力学不稳定，经促红细胞生成素、胃肠外铁剂、叶酸和大剂量类固醇治疗成功。