Mirjalili Fatemeh, Rezazadegan Mahsa, Jalilpiran Yahya, Mousavi Seyed Mohammad, Jafari Alireza, Mohajeri Seyed Amir Reza, Faghih Shiva
Department of Clinical Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Student Research Committee, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Nutr Cancer. 2022;74(4):1270-1278. doi: 10.1080/01635581.2021.1952448. Epub 2021 Jul 19.
There are few studies that evaluated the relationship between dietary diversity score (DDS) and risk of cancer. The purpose of this study was to examine the association of DDS with the risk of prostate cancer (PC) among Iranian men. This case-control study was performed among 60 cases with prostate cancer and 60 hospital-based controls. Anthropometric measurements were done and demographic information was recorded using standard protocols. A validated 160-item semi-quantitative food frequency questionnaire (FFQ) was used to assess usual dietary intakes. Also, Binary logistic regression was performed to estimate the risk of PC in relation to DDS. After controlling for several confounders (age, body mass index, physical activity, energy intake, job, education, and antihypertensive drugs usage) higher adherence to DDS (OR = 0.33; 95% CI (0.11-0.97)), fruits group (OR = 0.19; 95% CI (0.06-0.63)), and vegetables group (OR = 0.17; 95% CI (0.05 - 0.58)) were significantly associated with lower risk of PC. In contrast, greater adherence to the meat group (OR = 3.88; 95% CI (1.32-11.42)) was significantly associated with increased PC risk. Our results showed that adherence to a diet with higher DDS, especially higher amounts of fruits and vegetables and a lower amount of meat could decrease the risk of PC.
很少有研究评估饮食多样性评分（DDS）与癌症风险之间的关系。本研究的目的是探讨伊朗男性中DDS与前列腺癌（PC）风险之间的关联。这项病例对照研究在60例前列腺癌患者和60例医院对照中进行。采用标准方案进行人体测量并记录人口统计学信息。使用经过验证的160项半定量食物频率问卷（FFQ）评估日常饮食摄入量。此外，进行二元逻辑回归以估计与DDS相关的PC风险。在控制了几个混杂因素（年龄、体重指数、身体活动、能量摄入、工作、教育和抗高血压药物使用情况）后，更高的DDS依从性（OR = 0.33；95% CI（0.11 - 0.97））、水果组（OR = 0.19；95% CI（0.06 - 0.63））和蔬菜组（OR = 0.17；95% CI（0.05 - 0.58））与较低的PC风险显著相关。相反，更高的肉类组依从性（OR = 3.88；95% CI（1.32 - 11.42））与PC风险增加显著相关。我们的结果表明，坚持较高DDS的饮食，尤其是较多的水果和蔬菜以及较少的肉类，可以降低PC风险。
