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旧世界猴肝脏过氧化物酶体中的不溶性尿酸酶。

Insoluble uricase in liver peroxisomes of Old World monkeys.

作者信息

Fujiwara S, Nakashima K, Noguchi T

机构信息

Department of Biochemistry, Kyushu Dental College, Kitakyushu, Japan.

出版信息

Comp Biochem Physiol B. 1987;88(2):467-9. doi: 10.1016/0305-0491(87)90328-2.

Abstract
  1. Subcellular localization form and properties of liver uricase of Macaca fascicularis were examined. 2. Uricase was present as the insoluble form in the peroxisomal core. 3. Evidence was obtained to show that the peroxisomal core is uricase itself. 4. The number and mol. wts of the subunits of the enzyme were identical to those of rat liver uricase. 5. The same results were also obtained for liver uricase of Macaca fuscata.
摘要
  1. 对猕猴肝脏尿酸酶的亚细胞定位形式和特性进行了研究。2. 尿酸酶以不溶性形式存在于过氧化物酶体核心中。3. 有证据表明过氧化物酶体核心本身就是尿酸酶。4. 该酶亚基的数量和分子量与大鼠肝脏尿酸酶的相同。5. 对食蟹猴肝脏尿酸酶也得到了相同的结果。

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