Institut Charles Sadron, University of Strasbourg, CNRS UPR22, 23 rue du Loess, 67037 Strasbourg, France; Urgo Research Innovation and Development, 42 rue de Longvic, 21304 Chenôve Cedex, France.
Urgo Research Innovation and Development, 42 rue de Longvic, 21304 Chenôve Cedex, France.
Adv Colloid Interface Sci. 2021 Aug;294:102478. doi: 10.1016/j.cis.2021.102478. Epub 2021 Jun 29.
Hydrogel foams are an important sub-class of macroporous hydrogels. They are commonly obtained by integrating closely-packed gas bubbles of 10-1000 μm into a continuous hydrogel network, leading to gas volume fractions of more than 70% in the wet state and close to 100% in the dried state. The resulting wet or dried three-dimensional architectures provide hydrogel foams with a wide range of useful properties, including very low densities, excellent absorption properties, a large surface-to-volume ratio or tuneable mechanical properties. At the same time, the hydrogel may provide biodegradability, bioabsorption, antifungal or antibacterial activity, or controlled drug delivery. The combination of these properties are increasingly exploited for a wide range of applications, including the biomedical, cosmetic or food sector. The successful formulation of a hydrogel foam from an initially liquid foam template raises many challenging scientific and technical questions at the interface of hydrogel and foam research. Goal of this review is to provide an overview of the key notions which need to be mastered and of the state of the art of this rapidly evolving field at the interface between chemistry and physics.
水凝胶泡沫是大孔水凝胶的一个重要子类。它们通常通过将紧密堆积的 10-1000μm 气体气泡集成到连续水凝胶网络中而获得，从而在湿状态下使气体体积分数超过 70%，在干燥状态下接近 100%。由此产生的湿或干三维结构为水凝胶泡沫提供了广泛的有用特性，包括非常低的密度、优异的吸收特性、大的表面积与体积比或可调的机械特性。同时，水凝胶可提供生物降解性、生物吸收性、抗真菌或抗菌活性或控制药物释放。这些特性的组合越来越多地被用于广泛的应用领域，包括生物医学、化妆品或食品领域。从最初的液体泡沫模板成功制备水凝胶泡沫引发了在水凝胶和泡沫研究的界面处许多具有挑战性的科学和技术问题。这篇综述的目的是概述在化学和物理之间的这个快速发展领域的界面处需要掌握的关键概念和最先进技术。
