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Improvement of a SARS-CoV-2 vaccine by enhancing the conjugation efficiency of the immunogen to self-assembled nanoparticles.

作者信息

Zhang Xiantao, Yuan Yaochang, Wu Bolin, Wang Xuemei, Lin Yingtong, Luo Yuewen, Li Rong, Chen Tao, Deng Jieyi, Zhang Xu, Zou Fan, He Xin, Zhang Hui

机构信息

Institute of Human Virology, Key Laboratory of Tropical Disease Control of the Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agents and Immunotechnology, Engineering Research Center of Gene Vaccines of the Ministry of Education, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, Guangdong, China.

Qianyang Biomedical Research Institute, Guangzhou, Guangdong, 510063, China.

出版信息

Cell Mol Immunol. 2021 Aug;18(8):2042-2044. doi: 10.1038/s41423-021-00736-2. Epub 2021 Jul 19.

DOI:10.1038/s41423-021-00736-2
PMID:34282299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8287548/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb56/8322412/e3335bcc90db/41423_2021_736_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb56/8322412/e3335bcc90db/41423_2021_736_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb56/8322412/e3335bcc90db/41423_2021_736_Fig1_HTML.jpg

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A pneumonia outbreak associated with a new coronavirus of probable bat origin.
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