Koufen H, Hagel K H
Abteilung Allgemeine Psychiatrie, Albert-Ludwigs-Universität, Freiburg, Federal Republic of Germany.
Eur Arch Psychiatry Neurol Sci. 1987;237(1):2-7. doi: 10.1007/BF00385660.
A systematic 2 year follow-up study of EEG in 100 patients suffering from traumatic psychosis with amnesia lasting more than 1 week led to the following results. (1) EEG foci were demonstrated in 95% of cases, and bilaterally in 70%. Normalization occurred within 3 months in 48% of patients, with foci persisting for more than 2 years in 22% mostly in patients with traumatic epilepsy. Focal signs initially consisted of delta foci (85%) and finally of focal dysrhythmia (72%), with temporal localization increasing from 58% to 82%. EEG foci were associated with neurological focal symptoms in 49% of cases and skull fractures in 78%. (2) During psychosis a general slowing of EEG was constantly observed. Normalization occurred within 3 months in 28% of patients. Rarely slowing lasted longer than 6 months. (3) It took longer to normalize general slowing than EEG foci, but slowing disappeared more completely. The left preponderance of EEG foci in traumatic psychosis could not be confirmed, the hypothesis of a pathoplastic role of the speech dominant hemisphere was not proved.
对100例患有外伤性精神病且失忆持续超过1周的患者进行了为期2年的脑电图系统随访研究,结果如下。(1)95%的病例显示有脑电图病灶,双侧病灶占70%。48%的患者在3个月内脑电图恢复正常,22%的患者病灶持续超过2年,其中大多数为外伤性癫痫患者。病灶体征最初以δ波病灶为主(85%),最终以局灶性心律失常为主(72%),颞叶定位从58%增至82%。49%的病例中脑电图病灶与神经局灶症状相关,78%与颅骨骨折相关。(2)在精神病发作期间,持续观察到脑电图普遍减慢。28%的患者在3个月内恢复正常。很少有减慢持续超过6个月。(3)脑电图普遍减慢恢复正常所需时间比脑电图病灶长,但减慢消失得更彻底。外伤性精神病中脑电图病灶左侧优势无法得到证实,言语优势半球具有病理可塑性作用的假说未得到证实。