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1 型糖尿病患者的精神疾病、情绪困扰、血糖控制和慢性并发症。

Psychiatric illness, emotional distress, glycemic control and chronic complications in type 1 diabetes subjects.

机构信息

Programa de Endocrinologia, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brasil,

Divisão de Endocrinologia, Hospital Escola, Universidade Federal de Pelotas (UFPEL), Pelotas, RS, Brasil.

出版信息

Arch Endocrinol Metab. 2021 Nov 24;65(6):684-694. doi: 10.20945/2359-3997000000386. Epub 2021 Jul 16.

Abstract

OBJECTIVE

To assess the prevalence of psychiatric disorders in patients with type 1 diabetes mellitus (T1D) and to compare patients with and without psychiatric disorder.

METHODS

We made a cross-sectional study including patients with T1D assisted in the outpatient clinics of the Brazilian National Health System. To assess depression and anxiety, we used the PHQ-9 questionnaire and the DSM-5th edition criteria, respectively. B-PAID evaluated the level of emotional distress associated with diabetes; EAT-26, eating disorders; SCI-R, adherence to the proposed clinical treatment.

RESULTS

We analyzed 166 patients aged 33 (22-45.2) years, 53.6% female. The prevalence of depression and anxiety was 20.5% and 40.4%, respectively. HbA1c was worse in the depressed (9.0% vs. 8.4%, p = 0.008), in the anxious ones (9.0% vs. 8.3%, p = 0.012) and in the patients with high levels of B-PAID (8.8 % vs. 8.3 %, p = 0.009). There was no difference in the prevalence of complications related to diabetes.

CONCLUSION

The prevalence of psychiatric disorders and emotional distress related to diabetes was high in our population of T1D patients, and depression and high levels of B-PAID were associated with the worse glycemic control.

摘要

目的

评估 1 型糖尿病(T1D)患者的精神障碍患病率,并比较有和无精神障碍的患者。

方法

我们进行了一项横断面研究,纳入了在巴西国家卫生系统门诊就诊的 T1D 患者。为了评估抑郁和焦虑,我们分别使用 PHQ-9 问卷和 DSM-5 版标准。B-PAID 评估与糖尿病相关的情绪困扰程度;EAT-26 评估饮食障碍;SCI-R 评估对建议的临床治疗的依从性。

结果

我们分析了 166 名年龄为 33 岁(22-45.2)岁的患者,其中 53.6%为女性。抑郁和焦虑的患病率分别为 20.5%和 40.4%。HbA1c 在抑郁患者中更差(9.0%比 8.4%,p=0.008),在焦虑患者中更差(9.0%比 8.3%,p=0.012),在 B-PAID 水平较高的患者中更差(8.8%比 8.3%,p=0.009)。与糖尿病相关的并发症患病率没有差异。

结论

我们的 T1D 患者群体中精神障碍和与糖尿病相关的情绪困扰的患病率较高,抑郁和 B-PAID 水平较高与血糖控制较差相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c29/10065386/2f2d5846c947/2359-4292-aem-65-06-0684-gf01.jpg

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