From the Departments of Nuclear Medicine.
Pathology.
Clin Nucl Med. 2022 Jan 1;47(1):e45-e46. doi: 10.1097/RLU.0000000000003814.
68Ga-prostate-specific membrane antigen (PSMA) PET/CT is a well-established imaging modality in patients with prostate cancer; however, PSMA expression is also reported in the tumor-associated neovasculature, including but not limited to hepatocellular carcinoma, breast cancer, and renal cell carcinoma. Herein, we present 2 patients diagnosed with different histopathological subtypes of renal cell carcinoma who underwent 68Ga-PSMA PET/CT before surgery. Both cases have different PSMA expression characteristics and are presented along with pathological findings.
68Ga-前列腺特异性膜抗原(PSMA)PET/CT 是前列腺癌患者中一种成熟的影像学检查方法;然而,PSMA 表达也在肿瘤相关新生血管中被报道,包括但不限于肝细胞癌、乳腺癌和肾细胞癌。在此,我们介绍了 2 例在手术前接受 68Ga-PSMA PET/CT 检查的不同组织学亚型的肾细胞癌患者。这两个病例具有不同的 PSMA 表达特征,并结合病理发现进行了介绍。