Doctoral student, Department of Oral Health Sciences, School of Dentistry, University of Washington, Seattle, Wash.
Associate Professor, Director of Oral and Maxillofacial Radiology, College of Dental Medicine, Touro College, Hawthorne, NY.
J Prosthet Dent. 2023 Feb;129(2):247-250. doi: 10.1016/j.prosdent.2021.06.024. Epub 2021 Jul 18.
Osteopetrosis (marble bone disease) is a family of rare genetic disorders characterized by impaired osteoclast function leading to hyperdense, hypovascular, brittle bone. Typical imaging shows increased bone mass and thickened cortical and trabecular bone. Bones are more prone to fracture and osteomyelitis may develop. When considering dental implant placement in a patient with osteopetrosis, the potential for bony fracture and/or osteomyelitis should be considered along with the decreased likelihood of successful osseointegration because of hypovascularity. This clinical report describes an unusual imaging presentation and successful osseointegration of multiple dental implants supporting an implant-supported fixed mandibular prosthesis with long-term survival.
石骨症（大理石骨病）是一组罕见的遗传性疾病，其特征为破骨细胞功能受损，导致骨质高密度、低血管、脆弱。典型的影像学表现为骨量增加，皮质骨和松质骨增厚。骨骼更容易骨折，可能发展为骨髓炎。在考虑石骨症患者进行牙种植体植入时，应考虑到骨折和/或骨髓炎的潜在风险，以及由于低血管导致成功骨整合的可能性降低。本临床报告描述了一种不常见的影像学表现和多个牙种植体的成功骨整合，这些种植体支撑着下颌种植体固定修复体，长期存活。
