Udgirkar Suhas, Jain Shubham, Chandnani Sanjay, Rathi Pravin M, Contractor Qais, Kamat Rima
Department of Gastroenterology, Topiwala National Medical College and BYL Ch. Hospital, Mumbai, Maharashtra, India.
Int J Health Sci (Qassim). 2021 Jul-Aug;15(4):50-52.
Gastrointestinal (GI) tract manifestations of amyloid deposition include diarrhea, GI hemorrhage, steatorrhea, or constipation. Here, we report an elderly female presenting with GI hemorrhage due to gastric ulceration and 4-6 polypoidal lesions with intermittent ooze in the duodenum as a first presentation of primary systemic amyloidosis. The bleed was managed with proton-pump inhibitors and hemospray application. She received chemotherapy for multiple myeloma after stabilization. A high index of suspicion is needed to diagnose amyloidosis causing GI hemorrhage.
胃肠道淀粉样变性沉积的表现包括腹泻、胃肠道出血、脂肪泻或便秘。在此，我们报告一例老年女性，因胃溃疡导致胃肠道出血，十二指肠有4 - 6个息肉样病变并伴有间歇性渗血，这是原发性系统性淀粉样变性的首发表现。出血通过质子泵抑制剂和应用止血喷雾进行处理。病情稳定后，她接受了针对多发性骨髓瘤的化疗。诊断导致胃肠道出血的淀粉样变性需要高度的怀疑指数。
