前列腺癌根治性前列腺切除术后诊断出的偶发性慢性淋巴细胞白血病：一例报告。
Incidental chronic lymphocytic leukemia diagnosed following radical prostatectomy for prostate cancer: A case report.
作者信息
Tlili Ghassen, Ammar Houssem, Majdoub Wiem, Dziri Sonia, Farhat Waad, Acacha Emir, Rguez Arib, Ben Ahmed Khaled, Azzabi Awatef, Jaidane Mehdi
机构信息
Department of Urology, Sahloul Hospital, Sousse, Tunisia.
Department of Gastrointestinal Surgery, Sahloul Hospital, Sousse, Tunisia.
出版信息
Ann Med Surg (Lond). 2021 Jun 25;68:102516. doi: 10.1016/j.amsu.2021.102516. eCollection 2021 Aug.
BACKGROUND
chronic lymphocytic leukemia (CLL) patients have a high risk of occurrence of secondary cancers. This risk is three times higher for all cancers and eight times higher for skin cancer. The coexistence of CLL and adenocarcinoma of the prostate is rare.
CASE PRESENTATION
We report a case of a66-year-old man who underwent radical prostatectomy for prostate carcinoma. The final histopathological diagnosis of Gleason 7 adenocarcinoma of the prostate with incidental Rai stage I chronic lymphocytic leukemia (CLL) was made. No further investigations or treatment was offered due to the age and low disease stage. At the last follow-up of 12 months, the patient is alive, without disease progression for both lymphoma and prostate, with a PSA value of 0.03 ng/ml.
CONCLUSION
Early detection of lymphoma after radical prostatectomy will allow optimal management. The analysis of this link requires, therefore, additional investigations.
背景
慢性淋巴细胞白血病（CLL）患者发生继发性癌症的风险很高。所有癌症的这种风险高3倍，皮肤癌的风险高8倍。CLL与前列腺腺癌并存的情况很少见。
病例报告
我们报告一例66岁男性因前列腺癌接受根治性前列腺切除术。最终组织病理学诊断为Gleason 7级前列腺腺癌，偶然发现Rai I期慢性淋巴细胞白血病（CLL）。由于患者年龄和疾病分期较低，未进行进一步检查或治疗。在最后一次12个月的随访中，患者存活，淋巴瘤和前列腺均无疾病进展，前列腺特异性抗原（PSA）值为0.03 ng/ml。
结论
根治性前列腺切除术后早期发现淋巴瘤将有助于优化治疗。因此，对这种关联的分析需要进一步的研究。
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