粒子治疗协作组头颈亚委员会关于头颈部肿瘤治疗的粒子治疗共识指南。
PTCOG Head and Neck Subcommittee Consensus Guidelines on Particle Therapy for the Management of Head and Neck Tumors.
作者信息
Lin Alexander, Chang John H C, Grover Ryan S, Hoebers Frank J P, Parvathaneni Upendra, Patel Samir H, Thariat Juliette, Thomson David J, Langendijk Johannes A, Frank Steven J
机构信息
University of Pennsylvania, Philadelphia, PA, USA.
Oklahoma Proton Center, Oklahoma City, OK, USA.
出版信息
Int J Part Ther. 2021 Jun 25;8(1):84-94. doi: 10.14338/IJPT-20-00071.1. eCollection 2021 Summer.
PURPOSE
Radiation therapy is a standard modality in the treatment for cancers of the head and neck, but is associated with significant short- and long-term side effects. Proton therapy, with its unique physical characteristics, can deliver less dose to normal tissues, resulting in fewer side effects. Proton therapy is currently being used for the treatment of head and neck cancer, with increasing clinical evidence supporting its use. However, barriers to wider adoption include access, cost, and the need for higher-level evidence.
METHODS
The clinical evidence for the use of proton therapy in the treatment of head and neck cancer are reviewed here, including indications, advantages, and challenges.
RESULTS
The Particle Therapy Cooperative Group Head and Neck Subcommittee task group provides consensus guidelines for the use of proton therapy for head and neck cancer.
CONCLUSION
This report can be used as a guide for clinical use, to understand clinical trials, and to inform future research efforts.
目的
放射治疗是头颈部癌症治疗的标准方式，但会带来显著的短期和长期副作用。质子治疗具有独特的物理特性，可减少对正常组织的剂量，从而减少副作用。目前质子治疗正用于头颈部癌症的治疗，越来越多的临床证据支持其应用。然而，更广泛采用的障碍包括可及性、成本以及对更高级别证据的需求。
方法
本文回顾了质子治疗用于头颈部癌症治疗的临床证据，包括适应证、优势和挑战。
结果
粒子治疗协作组头颈部小组委员会任务组提供了质子治疗头颈部癌症的共识指南。
结论
本报告可作为临床应用指南，用于理解临床试验，并为未来的研究工作提供信息。
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