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多模态治疗肝癌:手术的作用。

Multimodal therapy for hepatocellular carcinoma: the role of surgery.

机构信息

"Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania,

出版信息

Eur Rev Med Pharmacol Sci. 2021 Jul;25(13):4470-4477. doi: 10.26355/eurrev_202107_26238.

DOI:10.26355/eurrev_202107_26238
PMID:34286489
Abstract

OBJECTIVE

Liver cancer is one of the widest spread malignancies in the world and its incidence is still on the rise. The surgical resection of liver cancer has become a widely performed procedure with considerably improved outcomes, low mortality rate, transfusions, and post-op bed stay.

MATERIALS AND METHODS

Our goal with this paper was to conduct a narrative review of the literature in regard to the surgical treatment of hepatocellular carcinoma (HCC).

RESULTS

There are various modalities of treatment for the HCC, e.g., hepatic resection, LT, or radiofrequency ablation (RFA) - the selection of a specific treatment regimen plays a decisive role in the survival rate of the patient and this, in turn, is guided by factors like size and distribution of lesion and the stage of malignancy. A more efficient patient selection for each treatment increases the survival rate of the patients in each subgroup.

CONCLUSIONS

Surgical procedures play a crucial role in treatment of hepatocellular carcinoma as part of a multimodal therapy.

摘要

目的

肝癌是世界上分布最广泛的恶性肿瘤之一,其发病率仍在上升。肝癌的手术切除已成为一种广泛开展的手术,其结果显著改善,死亡率、输血率和术后卧床时间均较低。

材料和方法

我们撰写本文的目的是对肝癌的外科治疗进行文献综述。

结果

肝癌的治疗方法有多种,例如肝切除术、肝移植或射频消融(RFA)-特定治疗方案的选择对患者的生存率起着决定性作用,而这反过来又受到病变的大小和分布以及恶性程度等因素的影响。对每种治疗方法进行更有效的患者选择可提高每个亚组患者的生存率。

结论

外科手术作为多模式治疗的一部分,在治疗肝细胞癌中起着关键作用。

相似文献

1
Multimodal therapy for hepatocellular carcinoma: the role of surgery.多模态治疗肝癌:手术的作用。
Eur Rev Med Pharmacol Sci. 2021 Jul;25(13):4470-4477. doi: 10.26355/eurrev_202107_26238.
2
Optimal application of stereotactic body radiotherapy and radiofrequency ablation treatment for different multifocal hepatocellular carcinoma lesions in patients with Barcelona Clinic Liver Cancer stage A4-B1: a pilot study.立体定向体部放疗和射频消融治疗巴塞罗那临床肝癌分期 A4-B1 不同多灶性肝癌病变的最佳应用:一项初步研究。
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Trans-arterial chemoembolization + radiofrequency ablation versus surgical resection in hepatocellular carcinoma - A meta-analysis.经动脉化疗栓塞术+射频消融术与手术切除治疗肝细胞癌的比较 - 一项荟萃分析。
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Improved clinical outcome using transarterial chemoembolization combined with radiofrequency ablation for patients in Barcelona clinic liver cancer stage A or B hepatocellular carcinoma regardless of tumor size: results of a single-center retrospective case control study.经导管动脉化疗栓塞联合射频消融治疗巴塞罗那临床肝癌分期 A 或 B 期肝细胞癌患者的临床结局改善,无论肿瘤大小:单中心回顾性病例对照研究结果。
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Liver resection for hepatocellular carcinoma in patients with hematological malignancies.血液恶性肿瘤患者的肝细胞癌肝切除术。
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引用本文的文献

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BMC Cancer. 2025 Jul 1;25(1):1040. doi: 10.1186/s12885-025-14425-0.
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The Financial Toxicity of Hepatopancreatobiliary Cancer: An Analysis of the 1997-2023 National Health Interview Survey.肝胰胆管癌的经济毒性:对1997 - 2023年国家健康访谈调查的分析
J Gastrointest Cancer. 2025 Apr 3;56(1):92. doi: 10.1007/s12029-025-01217-9.
3
Successful Multidisciplinary Treatment, Including Atezolizumab Plus Bevacizumab Biological Therapy, for Multiple Hepatocellular Carcinomas Adjacent to Major Vessels: A Case Report.
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