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通过能量色散X射线荧光分析测定模拟胃内容物中的有毒金属及一例汞中毒致死病例

The determination of toxic metals in simulated stomach contents by energy dispersive X-ray fluorescence analysis and a fatal case of mercury poisoning.

作者信息

Winstanley R, Patel I, Fischer E

机构信息

Forensic Science Laboratory, Chorley, Lancashire, U.K.

出版信息

Forensic Sci Int. 1987 Oct-Nov;35(2-3):181-7. doi: 10.1016/0379-0738(87)90054-5.

DOI:10.1016/0379-0738(87)90054-5
PMID:3428801
Abstract

Soup is used as a simulated stomach contents matrix to determine the lower level of detection for 16 metals. All of the metals can be detected at the levels which might be expected for acute fatal doses even if the stomach contents are considerably diluted. However where small doses are administered over a prolonged period this method may not be sufficiently sensitive. A case of fatal poisoning by the ingestion of mercuric chloride is described to illustrate the effectiveness of the method. In this case mercury was also detected and determined at highly significant levels in blood and liver by the same technique. This energy dispersive X-ray fluorescence (EDXRF) method is easy to use, rapid and non-destructive.

摘要

汤被用作模拟胃内容物基质,以确定16种金属的最低检测限。即使胃内容物被大量稀释,所有金属在急性致死剂量可能出现的水平下都能被检测到。然而,对于长时间摄入小剂量金属的情况,该方法可能不够灵敏。描述了一例因摄入氯化汞导致的致命中毒案例,以说明该方法的有效性。在这个案例中,通过相同技术在血液和肝脏中也检测到汞,且含量极高。这种能量色散X射线荧光(EDXRF)方法易于使用、快速且无损。

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