Dahlén Torsten, Zhao Jingcheng, Magnusson Patrik K E, Pawitan Yudi, Lavröd Jakob, Edgren Gustaf
Department of Medicine Solna, Clinical Epidemiology Division, Karolinska Institutet, Stockholm, Sweden.
Department of Hematology, Karolinska University Hospital, Stockholm, Sweden.
J Intern Med. 2022 Jan;291(1):95-100. doi: 10.1111/joim.13351. Epub 2021 Jul 20.
The occurrence of misattributed paternity has consequences throughout society with implications ranging from inheritance and royal succession to transplantation. However, its frequency in Sweden is unknown.
To estimate the contemporary frequency of misattributed paternity in Sweden.
The study was based on nationwide ABO blood group data and a nationwide register of familial relationships in Sweden. These data were analysed using both a frequentist Poisson model and the Bayesian Gibbs model. The conduct of the study was approved by the regional ethics committee in Stockholm, Sweden (reference numbers 2018/167-31 and 2019-04656).
Nearly two million mother-father-offspring family units were included. Overall, the frequency of misattributed paternity was estimated at 1.7% in both models. Misattributed paternity was more common among parents with low educational levels, and has decreased over time to a current 1%.
The misattributed paternity rate is similar to the rates in other West European populations. Apart from widespread societal implications, studies on heritability may consider misattributed paternity as a minor source of error.
亲子关系误认现象在整个社会都有影响，涉及从继承、王室继承到移植等诸多方面。然而，其在瑞典的发生频率尚不清楚。
估计瑞典当代亲子关系误认的频率。
该研究基于瑞典全国范围的ABO血型数据和全国性的家庭关系登记册。使用频率主义泊松模型和贝叶斯吉布斯模型对这些数据进行分析。该研究的开展获得了瑞典斯德哥尔摩地区伦理委员会的批准（参考编号2018/167 - 31和2019 - 04656）。
纳入了近200万个父母 - 子女家庭单元。总体而言，两种模型估计的亲子关系误认频率均为1.7%。亲子关系误认在受教育程度低的父母中更为常见，且随着时间推移已降至目前的1%。
亲子关系误认率与其他西欧人群的比率相似。除了广泛的社会影响外，关于遗传力的研究可能会将亲子关系误认视为一个较小的误差来源。
