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头颈部癌症放疗后 90 天死亡率:农村和城市患者的基于人群比较。

Ninety-day mortality after radiotherapy for head and neck cancer: Population-based comparison between rural and urban patients.

机构信息

Radiation Oncology, BC Cancer - Centre for the North, Prince George, British Columbia, Canada.

Department of Surgery, Radiation Oncology, University of British Columbia, Vancouver, British Columbia, Canada.

出版信息

Head Neck. 2021 Nov;43(11):3306-3313. doi: 10.1002/hed.26819. Epub 2021 Jul 21.

Abstract

BACKGROUND

This study assesses whether 90-day mortality differs between patients living in rural and urban areas, as lower access to supportive care services in rural areas could result in higher mortality.

METHODS

All patients with head and neck cancer (HNC) treated between 1998 and 2014 with radiotherapy in British Columbia were included. Patients were divided into rurality areas according to the Modified Statistics Canada (mSC) definition, which classifies a population <30 000 as rural and ≥30 000 as urban.

RESULTS

Five thousand five hundred and fifty-four patients were included in this study, of which 68% lived in urban centers. The 90-day mortality for rural versus urban patients were 3.0% and 3.9% (p = 0.09), respectively. Univariate and multivariate analyses showed no association with 90-day mortality and rurality.

CONCLUSION

After controlling for potentially confounding factors, we did not find a significant association between 90-day mortality and rurality in patients who were treated with radiotherapy for HNC in British Columbia.

摘要

背景

本研究评估了农村和城市地区患者的 90 天死亡率是否存在差异,因为农村地区获得支持性护理服务的机会较少可能导致死亡率较高。

方法

纳入了 1998 年至 2014 年间在不列颠哥伦比亚省接受放射治疗的所有头颈部癌症(HNC)患者。根据加拿大统计局修正定义(mSC)将患者分为农村地区和城市地区,mSC 将人口<30000 的地区定义为农村,人口≥30000 的地区定义为城市。

结果

本研究共纳入了 5554 名患者,其中 68%的患者居住在城市中心。农村地区与城市地区患者的 90 天死亡率分别为 3.0%和 3.9%(p=0.09)。单因素和多因素分析均未显示 90 天死亡率与农村地区之间存在关联。

结论

在控制了潜在的混杂因素后,我们没有发现不列颠哥伦比亚省接受 HNC 放射治疗的患者 90 天死亡率与农村地区之间存在显著关联。

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