Gopalarathinam K, Jeganathan P S, Anantharaman V, Namasivayam A
Department of Physiology, University of Madras, Taramani.
Indian J Physiol Pharmacol. 1987 Jul-Sep;31(3):178-83.
The effect of alcohols (ethanol and methanol) on rat electromyogram (E.M.G.) and neuromuscular latency were studied in thiopentone anesthetized albino rats. Both alcohols were given intraperitoneally (100 mg/100 g of body weight) to the respective groups and the controls received saline. Electromyographic signals were recorded from gastrocnemius muscle. For latency studies both the alcohols were given intravenously (iv) at a dose of 20 mg/100 g of body weight, and response to in situ sciatic nerve stimulation was studied before and after alcohol administration. Our results show that both ethanol and methanol induce spontaneous electromyographic signals and in addition produce changes in the latent period and the amplitude of the response.
在硫喷妥钠麻醉的白化大鼠中研究了醇类（乙醇和甲醇）对大鼠肌电图（E.M.G.）和神经肌肉潜伏期的影响。分别向相应组腹腔注射两种醇类（100毫克/100克体重），对照组注射生理盐水。从腓肠肌记录肌电信号。在潜伏期研究中，两种醇类均以20毫克/100克体重的剂量静脉注射（iv），并在给药前后研究对坐骨神经原位刺激的反应。我们的结果表明，乙醇和甲醇均可诱发自发肌电信号，此外还会使潜伏期和反应幅度发生变化。
