Wang Yao, Gao Ying, Chen Hai-Ruo, Liu Hong, Fu Xi, Yan Ran, You Feng-Ming, Li Zhuo-Hong
Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China.
Clin Med Insights Oncol. 2021 Jul 12;15:11795549211028571. doi: 10.1177/11795549211028571. eCollection 2021.
Here, we reported the rare case of primary pleural squamous cell carcinoma (PPSCC) in a 71-year-old male patient. After chemo and targeted therapies, the patient showed continuous tumor progression and clinical deterioration. Fortunately, the patient had a high expression level of PD-L1 (80%) in the tumor tissues. Ultimately, the patient survived for additional 6 months with camrelizumab treatment. In summary, camrelizumab may be a good candidate for the treatment of PPSCC, especially in tumors with high PD-L1 expression.
在此,我们报告了一例71岁男性原发性胸膜鳞状细胞癌(PPSCC)的罕见病例。经过化疗和靶向治疗后,患者肿瘤持续进展,临床症状恶化。幸运的是,患者肿瘤组织中PD-L1表达水平较高(80%)。最终,患者接受卡瑞利珠单抗治疗后又存活了6个月。总之,卡瑞利珠单抗可能是治疗PPSCC的良好选择,尤其是对于PD-L1高表达的肿瘤。