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垂直旁矢状半球切开术:经杏仁核传出纤维导致术后颞叶内侧癫痫发作 1 例报告。

Vertical parasagittal hemispherotomy: a case report of postoperative mesio-temporal seizures via amygdalofugal pathway.

机构信息

Pediatric Neurosurgery Department, Rothschild Foundation Hospital, Paris, France.

Department of Neurosurgery, CHRU Nancy, Nancy, France.

出版信息

Acta Neurochir (Wien). 2021 Oct;163(10):2833-2836. doi: 10.1007/s00701-021-04836-w. Epub 2021 Jul 21.

Abstract

Vertical parasagittal hemispherotomy (VPH) is a well-established surgical treatment which is proposed for children with widespread unilateral onset of intractable epileptic seizures. VPH allows to disconnect from a vertical transventricular approach all white matter fibers of the hemisphere around a central core including the thalamus. We present the case of a girl who underwent VPH for hemimegalencephaly in early infancy. Postoperatively, she developed unexpected seizures of mesio-temporal origin. Stereo-EEG provided arguments for an amygdalar origin. High-resolution MRI with tractography confirmed the presence of the amygdalo-fugal pathway to be responsible of epileptic discharges propagation. She became seizure-free after temporal resection.

摘要

垂直旁矢状半球切开术(VPH)是一种成熟的手术治疗方法,适用于广泛单侧起始的难治性癫痫发作的儿童。VPH 通过垂直经脑室入路,从中央核心周围的半球的所有白质纤维(包括丘脑)进行分离。我们报告了一例婴儿期行 VPH 治疗巨脑回畸形的女孩。术后,她出现了意料之外的颞叶起源的癫痫发作。立体脑电图提供了杏仁核起源的证据。高分辨率 MRI 与轨迹追踪术证实,杏仁核-传出通路的存在是癫痫放电传播的原因。行颞叶切除后,她的癫痫发作停止了。

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