Tan Chung Hong, Nomanbhay Saifuddin, Shamsuddin Abd Halim, Show Pau Loke
Institute of Sustainable Energy (ISE), Universiti Tenaga Nasional, Jalan Ikram-UNITEN, 43000 Kajang, Selangor Malaysia.
Department of Chemical and Environmental Engineering, Faculty of Science and Engineering, University of Nottingham Malaysia, Jalan Broga, 43500 Semenyih, Selangor Darul Ehsan Malaysia.
Indian J Microbiol. 2021 Sep;61(3):279-282. doi: 10.1007/s12088-021-00930-w. Epub 2021 Mar 23.
In our modern world, biotechnology products play important roles not only in our health and culture, but also various industries such as food, agriculture, sewage treatment, biofuels, nutraceuticals, and pharmaceuticals. Rapid technological advances in biotechnology over the last few decades have allowed industrial integration of mammalian cells (like the Chinese hamster ovary cells) and algae cells in pharmaceutical and biofuel industries to produce commercial products and valuable biomolecules. However, the cost of cell harvest and recovery can become expensive depending on the harvesting technique, degree of purification, and intended use of the end-products. This has led to numerous research in exploring and developing efficient harvesting techniques. Therefore, in this review, the popular harvesting techniques and their recent applications will be discussed.
在我们的现代世界中,生物技术产品不仅在我们的健康和文化方面发挥着重要作用,而且在食品、农业、污水处理、生物燃料、营养保健品和制药等各个行业也发挥着重要作用。过去几十年生物技术的快速技术进步使得哺乳动物细胞(如中国仓鼠卵巢细胞)和藻类细胞在制药和生物燃料行业实现工业整合,以生产商业产品和有价值的生物分子。然而,根据收获技术、纯化程度和最终产品的预期用途,细胞收获和回收的成本可能会变得很高。这导致了在探索和开发高效收获技术方面的大量研究。因此,在本综述中,将讨论流行的收获技术及其最新应用。