Mohr Kieran S, Carr Niamh, Georgel Rachel, Kelly Simon P
Cognitive Neural Systems Lab, School of Electrical and Electronic Engineering and UCD Centre for Biomedical Engineering, University College Dublin, Dublin 4, Ireland.
Cereb Cortex Commun. 2020 Aug 5;1(1):tgaa045. doi: 10.1093/texcom/tgaa045. eCollection 2020.
Spatial attention modulations of initial afferent activity in area V1, indexed by the first component "C1" of the human visual evoked potential, are rarely found. It has thus been suggested that early modulation is induced only by special task conditions, but what these conditions are remains unknown. Recent failed replications-findings of no C1 modulation using a certain task that had previously produced robust modulations-present a strong basis for examining this question. We ran 3 experiments, the first to more exactly replicate the stimulus and behavioral conditions of the original task, and the second and third to manipulate 2 key factors that differed in the failed replication studies: the provision of informative performance feedback, and the degree to which the probed stimulus features matched those facilitating target perception. Although there was an overall significant C1 modulation of 11%, individually, only experiments 1 and 2 showed reliable effects, underlining that the modulations do occur but not consistently. Better feedback induced greater P1, but not C1, modulations. Target-probe feature matching had an inconsistent influence on modulation patterns, with behavioral performance differences and signal-overlap analyses suggesting interference from extrastriate modulations as a potential cause.
由人类视觉诱发电位的第一个成分“C1”所索引的V1区初始传入活动的空间注意调制很少被发现。因此，有人提出早期调制仅由特殊任务条件诱发，但这些条件是什么仍然未知。最近的失败复现——使用先前产生强烈调制的特定任务却未发现C1调制的结果——为研究这个问题提供了有力依据。我们进行了3个实验，第一个实验更精确地复现原始任务的刺激和行为条件，第二个和第三个实验则操纵失败复现研究中不同的两个关键因素：提供信息性的表现反馈，以及探测刺激特征与促进目标感知的特征相匹配的程度。虽然总体上存在11%的显著C1调制，但单独来看，只有实验1和实验2显示出可靠的效果，这表明调制确实会发生，但并非始终如此。更好的反馈会诱发更大的P1调制，但不会诱发更大的C1调制。目标-探测特征匹配对调制模式有不一致的影响，行为表现差异和信号重叠分析表明，来自纹外调制的干扰是一个潜在原因。
