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全身麻醉期间长时间应用腹部手术牵开器的心肺效应:一项前瞻性观察性对比研究

Cardiopulmonary effects of prolonged surgical abdominal retractors application during general anesthesia: a prospective observational comparative study.

作者信息

Ghanem Mohamed A, El-Hefnawy Ahmed S

机构信息

Mansoura University, Faculty of Medicine, Anesthesia Department, Anesthesia and Surgical Intensive Care, Almançora, Egypt.

Mansoura University, Faculty of Medicine, Urology Surgery, Urology and Nephrology Center, Almançora, Egypt.

出版信息

Braz J Anesthesiol. 2023 May-Jun;73(3):291-300. doi: 10.1016/j.bjane.2021.06.019. Epub 2021 Jul 21.

Abstract

INTRODUCTION

Increasing abdominal pressures could affect pulmonary compliance and cardiac performance, a fact based on which the aim of the present study to detect the cardiopulmonary burden of multiple retractors application during supine versus lateral abdominal surgeries. We hypothesized that surgical ring multiple retractors application would affect the pulmonary and cardiac functions during both lateral and supine abdominal surgeries.

METHODS

Prospective observational comparative study on forty surgical patients subdivided into two groups twenty each, comparing pulmonary compliance and cardiac performance before, during and after retractors application, group (S) supine position cystectomy surgery, and group (L) lateral position nephrectomy surgery under general anesthesia, Composite 1ry outcome; dynamic compliance C-dyn and cardiac index CI and Other outcome variables ICON cardio-meter were also recorded.

RESULTS

C-dyn and C-stat were significantly decreased late during retractor application in lateral compared to supine surgery with significant decrease compared to basal values all over the surgical time. CI was significantly increased after retractor removal in both of the study groups compared to basal values. PAWP was significantly increased in -lateral compared to supine surgery -with significant increase compared to basal value all over the surgical time in both of the study groups. significant increase in DO2I compared to basal value during both supine and lateral positions.

CONCLUSION

Surgical retraction results in a short-lived significant decreases in lung compliance and cardiac output particularly during the lateral-kidney position than the supine position compliance.

摘要

引言

腹压增加会影响肺顺应性和心脏功能,基于这一事实,本研究旨在检测仰卧位与侧卧位腹部手术中使用多个牵开器时的心肺负担。我们假设在侧卧位和仰卧位腹部手术中使用手术环形多个牵开器会影响肺和心脏功能。

方法

对40例手术患者进行前瞻性观察性比较研究,分为两组,每组20例,比较牵开器使用前、使用期间和使用后的肺顺应性和心脏功能,(S)组为仰卧位膀胱切除术,(L)组为侧卧位肾切除术,均在全身麻醉下进行,记录复合主要结局指标动态顺应性(C-dyn)和心脏指数(CI)以及其他结局变量(ICON心排血量计)。

结果

与仰卧位手术相比,侧卧位手术在牵开器使用后期C-dyn和静态顺应性(C-stat)显著降低,且在整个手术过程中与基础值相比均显著降低。与基础值相比,两个研究组在牵开器移除后CI均显著增加。与仰卧位手术相比,侧卧位手术中肺动脉楔压(PAWP)显著升高,且在两个研究组的整个手术过程中与基础值相比均显著升高。与基础值相比,仰卧位和侧卧位时氧输送指数(DO2I)均显著增加。

结论

手术牵拉导致肺顺应性和心输出量短暂显著下降,特别是在侧卧位肾脏手术时比仰卧位时顺应性下降更明显。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0471/10240226/029a3c09461e/gr1.jpg

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