Department of Chemical & Biological Sciences and Laboratory of Nanotechnology and Molecular Biomedicine Research, School of Sciences, Universidad de las Américas Puebla, San Andrés Cholula, Puebla 72810, Mexico.
Molecules. 2021 Jul 9;26(14):4186. doi: 10.3390/molecules26144186.
Hierarchically porous materials, such as wrinkled mesoporous silica (WMS), have gained interest in the last couple of decades, because of their wide range of applications in fields such as nanomedicine, energy, and catalysis. The mechanism of formation of these nanostructures is not fully understood, despite various groups reporting very comprehensive studies. Furthermore, achieving particle diameters of 100 nm or less has proven difficult. In this study, the effects on particle size, pore size, and particle morphology of several co-solvents were evaluated. Additionally, varying concentrations of acid during synthesis affected the particle sizes, yielding particles smaller than 100 nm. The morphology and physical properties of the nanoparticles were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and dynamic light scattering (DLS). Homogeneous and spherical WMS, with the desired radial wrinkle morphology and particle sizes smaller than 100 nm, were obtained. The effect of the nature of the co-solvents and the concentration of acid are explained within the frame of previously reported mechanisms of formation, to further elucidate this intricate process.
分层多孔材料，如皱状介孔硅（WMS），由于其在纳米医学、能源和催化等领域的广泛应用而在过去几十年中受到关注。尽管各个小组都报告了非常全面的研究，但这些纳米结构的形成机制仍未完全理解。此外，实现粒径为 100nm 或以下一直被证明是困难的。在这项研究中，评估了几种共溶剂对粒径、孔径和颗粒形态的影响。此外，在合成过程中改变酸的浓度会影响颗粒尺寸，得到小于 100nm 的颗粒。通过 X 射线衍射（XRD）、傅里叶变换红外光谱（FTIR）、扫描电子显微镜（SEM）和动态光散射（DLS）对纳米颗粒的形貌和物理性质进行了表征。得到了具有所需的径向皱折形貌和小于 100nm 粒径的均匀和球形 WMS。在以前报道的形成机制的框架内解释了共溶剂的性质和酸浓度的影响，以进一步阐明这一复杂的过程。
