Cutis Academy of Cutaneous Sciences, Bangalore, India.
Int J Dermatol. 2021 Dec;60(12):1553-1560. doi: 10.1111/ijd.15761. Epub 2021 Jul 24.
Ear keloids are benign, fibrous proliferations due to excessive collagen synthesis and deposition. It is a popular practice to pierce earlobes for decorative earrings and adornment; this might trigger the keloid process. Although there are varied treatment modalities, it is unsatisfactory and has always been a challenge. The aim is to evaluate the efficacy of surgical treatment with intralesional therapy in auricular keloids.
We included 30 patients with 45 keloids over the ear. Patients were evaluated (including detailed history, complete physical and local examination), and photographs and written informed consent were taken. They were treated with: excision and closure, intralesional and/or surface cryotherapy, ablative laser, intralesional steroids, and 5-fluorouracil. Excision and closure, and intralesional cryotherapy were done under local anesthesia. Closure was done after intramarginal excision with or without raising auto flaps, followed by intraoperative intralesional steroids to margins. Recurrence was assessed at 3 weeks, 3 months, 6 months, and 1 year.
The age group of patients ranged from 14 to 57 years. A total of 32 out of 45 (71.1%) keloids were excised and were combined with intraoperative and postoperative intralesional steroid injection, with sessions depending on the patient's response. Eight (17.7%) and five (11.1%) keloids were treated using intralesional cryotherapy and only intralesional steroids, respectively. A total of 16.6% of patients had recurrence with one patient having recurrence of bilateral earlobes keloid.
Keloidectomy with intraoperative and postoperative intralesional steroid injections has been very effective in the treatment of ear keloids. Different treatment modalities act synergistically, but excision surgery gives good results as it aims at maintaining ear architecture.
耳瘢痕疙瘩是由于胶原过度合成和沉积导致的良性纤维性增生。为了装饰和美化耳垂而穿孔是引发瘢痕疙瘩的常见原因。尽管有多种治疗方法,但效果并不理想,一直是一个挑战。本研究旨在评估耳瘢痕疙瘩切除联合瘤内治疗的疗效。
我们纳入了 30 名 45 个耳瘢痕疙瘩患者。对患者进行评估(包括详细病史、全面体格检查和局部检查),并拍摄照片和获得书面知情同意书。患者接受以下治疗:切除和缝合、瘤内和/或表面冷冻疗法、消融性激光、瘤内皮质类固醇和 5-氟尿嘧啶。切除和缝合、冷冻疗法在局部麻醉下进行。切除边缘后,采用边缘切除或自体皮瓣转移进行缝合,并在术中向边缘内注射皮质类固醇。在术后 3 周、3 个月、6 个月和 1 年评估复发情况。
患者年龄为 14-57 岁。共切除 45 个瘢痕疙瘩中的 32 个,并结合术中及术后瘤内皮质类固醇注射,根据患者的反应进行治疗。8 个(17.7%)和 5 个(11.1%)瘢痕疙瘩分别采用瘤内冷冻疗法和仅瘤内皮质类固醇治疗。16.6%的患者复发,其中 1 例双侧耳垂瘢痕疙瘩复发。
耳瘢痕疙瘩切除联合术中及术后瘤内皮质类固醇注射治疗非常有效。不同的治疗方法具有协同作用,但切除手术可获得良好的效果,因为它旨在维持耳部结构。