Feng Huimin, Jin Zhanguo, Liu Hongjin, Xu Xianrong, Zhai Lihong, Wang Meng, Zhang Mengdie
Aerospace Balance Medical Center，Chinese PLA Air Force Medical Center，Beijing，100142，China.
Department of Medical Identification，Chinese PLA Air Force Medical Center.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Jun;35(6):525-528. doi: 10.13201/j.issn.2096-7993.2021.06.009.
To compare and analyze the clinical features of family clustered vestibular migraine（FCVM） and sporadic vestibular migraine（SVM）. A total of 118 patients with vestibular migraine were selected and divided into FCVM group（66 cases） and SVM group（52 cases）, and the clinical features such as age, the form of symptoms, provoking and relieving factors, audiological manifestations, sequelae and complications, were compared and analyzed. The onset of headache in FCVM group was earlier than that in SVM group （[23.88±11.45] years old and [28.77±11.85] years old, χ²=2.267, =0.025） with a longer interval between headache and vertigo attack （[13.11±10.08] years old and [8.50±9.26] years old, χ²=2.554, =0.012）.Patients with positional vertigo in the FCVM group were more than those in the SVM group （12[18.2%] and 0[0], χ²=3.171, =0.002）. Mental anxiety（<0.001）, neck stiffness（=0.028）, and concentration difficulties（=0.001） were more common in patients with FCVM at the end of the episode than in patients with SVM. Comorbid primary motion sickness combined was more common in FCVM group than in SVM group（49 cases[74.2%] and 25 cases[48.1%], χ²=2.906, =0.004）. The onset of FCVM is earlier and the prognosis is often poor. Primary motion sickness can be used as a reference for the early diagnosis of FCVM.
比较和分析家族聚集性前庭性偏头痛（FCVM）和散发性前庭性偏头痛（SVM）的临床特征。选取118例前庭性偏头痛患者，分为FCVM组（66例）和SVM组（52例），比较分析两组患者的年龄、症状形式、诱发及缓解因素、听力学表现、后遗症及并发症等临床特征。FCVM组头痛起病年龄早于SVM组（分别为[23.88±11.45]岁和[28.77±11.85]岁，χ²=2.267，P=0.025），头痛与眩晕发作的间隔时间更长（分别为[13.11±10.08]年和[8.50±9.26]年，χ²=2.554，P=0.012）。FCVM组位置性眩晕患者多于SVM组（分别为12例[18.2%]和0例[0]，χ²=3.171，P=0.002）。发作末期，FCVM患者精神焦虑（P<0.001）、颈部僵硬（P=0.028）和注意力不集中（P=0.001）比SVM患者更常见。FCVM组合并原发性晕动病比SVM组更常见（分别为49例[74.2%]和25例[48.1%]，χ²=2.906，P=0.004）。FCVM起病早且预后往往较差。原发性晕动病可作为FCVM早期诊断的参考依据。
