Cai Li, Wang Lixian, Guan Xuhua, Wang Lei, Hu Xinyi, Wu Yang, Tong Yeqing, Wang Peigang
School of Health Sciences, Wuhan University, Wuhan, 430071, People's Republic of China.
Wuhan Center for Disease Control and Prevention, Wuhan, 430015, People's Republic of China.
Infect Drug Resist. 2021 Jul 17;14:2753-2762. doi: 10.2147/IDR.S314881. eCollection 2021.
The study aimed to timely grasp the epidemiologic status of rabies in Central China from 2013 to 2018 and provide scientific evidence for the implementation of follow-up prevention and control measures.
We initiated a retrospective observational and descriptive study of bite-related injuries data and rabies disease data in Hubei province from 2013 to 2018, managed by the Center for Disease Control and Prevention.
A total of 2,028,691 individuals were exposed to bites from 2013 to 2018, of which 221 were diagnosed with rabies and deceased. Among those cases, the incubation periods of rabies varied from 3 days to 18,406 days, which has been shown to be statistically associated with where the infected person was exposed and whether the wound care has been conducted.
Epidemiological studies have shown that from 2013 to 2018, the current situation of rabies in Central China is still severe. The case fatality rate keeps virtually 100%. The rural population is still the most vulnerable group to rabies, characterized by a high exposure ratio and low treatment rate as well as poor vaccination compliance. Hoewever, larger populations are warranted to validate our findings.
本研究旨在及时掌握2013年至2018年华中地区狂犬病的流行病学状况,为后续防控措施的实施提供科学依据。
我们对湖北省疾病预防控制中心管理的2013年至2018年与咬伤相关的伤害数据和狂犬病疾病数据开展了一项回顾性观察性描述性研究。
2013年至2018年共有2,028,691人暴露于咬伤,其中221人被诊断为狂犬病并死亡。在这些病例中,狂犬病的潜伏期从3天到18,406天不等,已证明这与感染者的暴露地点以及是否进行了伤口处理在统计学上相关。
流行病学研究表明,2013年至2018年,华中地区狂犬病的现状仍然严峻。病死率几乎保持在100%。农村人口仍然是狂犬病最脆弱的群体,其特点是暴露率高、治疗率低以及疫苗接种依从性差。然而,需要更多人群来验证我们的研究结果。