Fan Haipeng, Fei Ruihua, Guo Chunwen, Li Yutang, Yan Cairong, Chen Fengshou, Zhang Yong
Department of Emergency Intensive Care Unit, First Hospital of Quanzhou Affiliated to Fujian Medical University Quanzhou, Fujian Province, China.
Department of Oncology Radiotherapy, First Hospital of Quanzhou Affiliated to Fujian Medical University Quanzhou, Fujian Province, China.
Am J Transl Res. 2021 Jun 15;13(6):6817-6826. eCollection 2021.
This study aimed to observe the application effect of emergency treatment mode of damage-control orthopedics (DCO) in pelvic fracture complicated with multiple fractures.
Ninety-four patients with pelvic fracture complicated with multiple fractures in our hospital were recruited and divided into two groups according to the random number table method, with 47 cases in each group. Patients in the control group received traditional methods for emergency treatment (early complete treatment), and patients in the research group received DCO for emergency treatment (treatment performed in stages according to patient's physiological tolerance, with simplified initial surgery, followed by ICU resuscitation, and finally definitive surgery). The two groups were compared in terms of mortality, the incidence of acidosis and hypothermia three days after the first surgery, surgery-related indexes (time of the first surgery, blood transfusion volume, intraoperative blood loss, recovery time of temperature, and length of hospital stay), coagulation function indexes (activated partial thromboplastin time (APTT), thrombin time (TT), prothrombin time (PT) and fibrinogen (FIB)), postoperative reduction of fracture, complication rate, and quality of life.
The incidences of acidosis, hypothermia, and mortality three days after the first surgery in the research group were lower than those in the control group (P<0.05). Compared with the control group, the research group experienced shorter time of the first surgery, less intraoperative blood transfusion volume, less intraoperative blood loss, shorter recovery time of body temperature, and shorter length of hospital stay (P<0.05). Seven days after surgery, PT, TT and APTT decreased and FIB increased in both groups (P<0.05), PT, TT and APTT in the research group were lower than those in the control group (P<0.05), while FIB was higher (P<0.05). The good rate of reduction in the research group was higher than that in the control group (P=0.025). The incidence of complications in the research group was lower than that in the control group (P=0.049). Six months after surgery, the scores of physiological function (PF), body pain (BP), role physical (RP), emotional function (EF), social function (SF), vitality, and general health (GH) of the research group were higher than those of the control group (P<0.05), but there was no significant difference in mental health (MH) between the two groups (P>0.05).
The emergency treatment mode of DCO is effective in pelvic fracture complicated with multiple fractures, which can effectively improve postoperative reduction of patients, improve the coagulation function, reduce complications, and improve the quality of life.
本研究旨在观察损伤控制骨科(DCO)急诊治疗模式在骨盆骨折合并多发骨折中的应用效果。
选取我院94例骨盆骨折合并多发骨折患者,按随机数字表法分为两组,每组47例。对照组患者接受传统急诊治疗方法(早期完全治疗),研究组患者接受DCO急诊治疗(根据患者生理耐受情况分阶段进行治疗,初期手术简化,随后进行重症监护病房复苏,最后进行确定性手术)。比较两组患者的死亡率、首次手术后3天酸中毒和体温过低的发生率、手术相关指标(首次手术时间、输血量、术中出血量、体温恢复时间和住院时间)、凝血功能指标(活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、凝血酶原时间(PT)和纤维蛋白原(FIB))、术后骨折复位情况、并发症发生率及生活质量。
研究组首次手术后3天酸中毒、体温过低及死亡率均低于对照组(P<0.05)。与对照组相比,研究组首次手术时间更短、术中输血量更少、术中出血量更少、体温恢复时间更短、住院时间更短(P<0.05)。术后7天,两组PT、TT及APTT均降低,FIB升高(P<0.05),研究组PT、TT及APTT低于对照组(P<0.05),而FIB高于对照组(P<0.05)。研究组骨折复位优良率高于对照组(P=0.025)。研究组并发症发生率低于对照组(P=0.049)。术后6个月,研究组生理功能(PF)、身体疼痛(BP)、角色功能(RP)、情感功能(EF)、社会功能(SF)、活力及总体健康(GH)评分均高于对照组(P<0.05),但两组心理健康(MH)评分差异无统计学意义(P>0.05)。
DCO急诊治疗模式应用于骨盆骨折合并多发骨折有效,可有效提高患者术后骨折复位情况,改善凝血功能,减少并发症,提高生活质量。