Liu Ming-Xing, Zhong Jun, Xia Lei, Dou Ning-Ning, Shi Juanhong
Department of Neurosurgery, Qingdao Municipal Hospital, Qingdao, People's Republic of China.
Department of Neurosurgery, XinHua Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, People's Republic of China.
J Neurol Surg B Skull Base. 2021 Jul;82(Suppl 3):e295-e299. doi: 10.1055/s-0040-1710520. Epub 2020 May 19.
Although microvascular decompression (MVD) has been widely accepted as an effective treatment of trigeminal neuralgia (TN), some patients have not been cured. To improve the postoperative outcome, the surgical procedure should be further refined. This is a retrospective study. Present study conducted at a cranial nerve disorder center. Clinical data were collected from patients with TN who had undergone surgery in our center, including 685 who had undergone traditional MVD and 576 who had undergone the "MVD plus" procedure, in which any vessel attached to the trigeminal nerve was freed away ("nerve-combing"), which was followed by intraoperative neurolysis. Postoperative outcomes and complications in the two groups were compared. Among patients who underwent traditional MVD, the rates of immediate relief and 1-year relief were 89.9 and 86.9%, respectively; among patients who underwent MVD plus group, these rates were 95.1 and 94.6%, respectively ( = 0.05). Patients who underwent MVD plus initially exhibited a higher rate of facial numbness ( < 0.05), but this finding decreased over time and reached the same level as that in the traditional MVD group within 3 months ( > 0.05). Sufficient MVD with nerve-combing for the treatment of TN may produce a high rate of cure with less recurrence.
尽管微血管减压术(MVD)已被广泛认可为治疗三叉神经痛(TN)的有效方法,但仍有部分患者未能治愈。为改善术后效果,手术操作应进一步优化。
这是一项回顾性研究。
本研究在一家颅神经疾病中心开展。
收集了在本中心接受手术的TN患者的临床资料,其中685例接受了传统MVD手术,576例接受了“MVD+”手术,即在游离附着于三叉神经的任何血管(“神经梳理”)后进行术中神经松解。
比较了两组患者的术后效果和并发症。
在接受传统MVD手术的患者中,即刻缓解率和1年缓解率分别为89.9%和86.9%;在接受“MVD+”手术的患者中,这些比率分别为95.1%和94.6%(P=0.05)。接受“MVD+”手术的患者最初面部麻木发生率较高(P<0.05),但随着时间推移这一情况有所下降,3个月内达到与传统MVD组相同水平(P>0.05)。
充分的MVD联合神经梳理治疗TN可能会有较高的治愈率且复发率较低。