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经圆孔穿刺射频热凝治疗孤立性上颌神经原发性三叉神经痛的长期随访。

Long-term Follow-up of Patients Treated with Percutaneous Radiofrequency Thermocoagulation via the Foramen Rotundum for Isolated Maxillary Nerve Idiopathic Trigeminal Neuralgia.

机构信息

Pain Department, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.

Pain Medical Institute of Gannan Medical University, Ganzhou, China.

出版信息

Pain Med. 2019 Jul 1;20(7):1370-1378. doi: 10.1093/pm/pnz006.

Abstract

OBJECTIVE

The purpose of this study is to evaluate the effectiveness and safety of percutaneous radiofrequency thermocoagulation (PRT) via the foramen rotundum (FR) for the treatment of isolated maxillary (V2) idiopathic trigeminal neuralgia (ITN) and assess the appropriate puncture angle through the anterior coronoid process to reach the FR.

METHODS

Between January 2011 and October 2016, 87 patients with V2 ITN refractory to conservative treatment were treated by computed tomography (CT)-guided PRT via the FR at our institution. The outcome of pain relief was assessed by the visual analog scale (VAS) and Barrow Neurological Institute (BNI) pain grade and grouped as complete pain relief (BNI grades I-III) or unsuccessful pain relief (BNI grades IV-V). Recurrence and complications were also monitored and recorded. The puncture angle for this novel approach was assessed based on intraoperative CT images.

RESULTS

Of the 87 treated patients, 85 (97.7%) achieved complete pain relief, and two patients (2.3%) experienced unsuccessful pain relief immediately after operation. During the mean follow-up period of 44.3 months, 15 patients (17.2%) experienced recurring pain. No severe complications occurred, except for hypoesthesia restricted to the V2 distribution in all patients (100%) and facial hematoma in 10 patients (11.5%). The mean puncture angle to reach the FR was 33.6° ± 5.7° toward the sagittal plane.

DISCUSSION

CT-guided PRT via the FR for refractory isolated V2 ITN is effective and safe and could be a rational therapy for patients with V2 ITN.

摘要

目的

本研究旨在评估经圆孔(FR)行经皮射频热凝术(PRT)治疗孤立性上颌(V2)原发性三叉神经痛(ITN)的有效性和安全性,并评估通过前冠状突到达 FR 的合适穿刺角度。

方法

2011 年 1 月至 2016 年 10 月,我院对 87 例经保守治疗无效的 V2 ITN 患者行 CT 引导下 FR 内 PRT 治疗。采用视觉模拟评分(VAS)和巴罗神经研究所(BNI)疼痛分级评估疼痛缓解效果,并分为完全缓解(BNI 分级 I-III)或疼痛缓解失败(BNI 分级 IV-V)。还监测和记录了复发和并发症。根据术中 CT 图像评估该新方法的穿刺角度。

结果

87 例治疗患者中,85 例(97.7%)完全缓解疼痛,2 例(2.3%)术后即刻疼痛缓解失败。在平均 44.3 个月的随访期间,15 例(17.2%)患者出现疼痛复发。除所有患者(100%)均出现局限于 V2 分布的感觉迟钝和面血肿 10 例(11.5%)外,无严重并发症发生。到达 FR 的平均穿刺角度为矢状面 33.6°±5.7°。

讨论

经 FR 行 CT 引导 PRT 治疗难治性孤立性 V2 ITN 有效且安全,可为 V2 ITN 患者提供一种合理的治疗方法。

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