关节镜下清创保守治疗 Kellgren-Lawrence I-III 级膝关节骨关节炎的中期疗效
Medium-term efficacy of arthroscopic debridement conservative treatment for knee osteoarthritis of Kellgren-Lawrence grades I-III.
作者信息
Lv Bo, Huang Kai, Chen Jun, Wu Zhuo-Yi, Wang Hua
机构信息
Department of Orthopaedics, Shanghai Jing'an District Zhabei Central Hospital, Shanghai 200070, China.
出版信息
World J Clin Cases. 2021 Jul 6;9(19):5102-5111. doi: 10.12998/wjcc.v9.i19.5102.
BACKGROUND
Arthroscopic debridement is a mature treatment for knee osteoarthritis (KOA). Due to the differences in the research subjects, methods, and efficacy evaluation indexes, there are great differences in the surgical efficacy reported in the literature.
AIM
To compare the medium-term efficacy of arthroscopic debridement and conservative treatment for KOA of Kellgren-Lawrence grades I-III.
METHODS
Patients with KOA of Kellgren-Lawrence grades I-III who were admitted to the orthopedic clinic of our hospital from July 2018 to December 2018 and agreed to undergo arthroscopic surgery were included in an arthroscopic debridement group, and those who refused surgical treatment were included in a conservative treatment group. Gender, age, body mass index (BMI), side of KOA, American hospital for special surgery knee score (HSS score) before treatment, visual analogue scale (VAS) score during walking and rest before treatment, conservative treatment content, and surgical procedure were recorded. Outpatient visits were conducted at the 1, 3, 6, 12, and 24 mo after treatment in the two groups. The changes of HSS score and VAS score in each group before and after treatment were statistically analyzed, and the differences of HSS score and VAS score in different treatment stages between the two groups were also compared.
RESULTS
In the conservative treatment group, there were 80 patients with complete follow-up data, including 20 males and 60 females, aged 58.75 ± 14.66 years old. And in the knee arthroscopic debridement group, there were 98 patients with complete follow-up data, including 24 males and 74 females, aged 59.27 ± 14.48 years old. There was no statistically significant difference in the general data (gender, age, BMI, side of KOA, Kellgren-Lawrence grade distribution, HSS score, and VAS score) between the two groups before treatment. The HSS scores of the conservative treatment group at the 1, 3, 6, 12, and 24 mo after treatment were significantly higher than that before treatment ( < 0.05). There was no statistical difference in HSS score of the conservative treatment group among the 1, 3, 6, 12, and 24 mo ( > 0.05). The HSS score of the knee arthroscopic debridement group at the 1 mo after surgery was significantly higher than that before surgery ( < 0.05). HSS scores of the knee arthroscopic debridement group at the 3, 6, 12, and 24 mo were significantly higher than those before surgery and at the 1 mo after surgery ( < 0.05). There were no statistically significant differences in HSS scores at the 3, 6, 12, and 24 mo after surgery ( > 0.05). HSS scores at the 3, 6, 12, and 24 mo were significantly higher in the arthroscopic debridement group than in the conservative treatment group ( < 0.05). There was no statistical difference in HSS scores between the two groups before treatment and at the 1 mo of follow-up ( > 0.05). VAS scores during walking and rest were significantly decreased in both groups, and the VAS score during rest was significantly lower in the arthroscopic debridement group than in the conservative treatment group, but there was no significant difference in the VAS score during walking between the two groups after treatment.
CONCLUSION
Compared with conservative treatment, arthroscopic debridement can significantly improve the knee resting pain and knee functional status of patients with KOA of Kellgren-Lawrence grades I-III within 2 years after treatment.
背景
关节镜下清创术是治疗膝关节骨关节炎(KOA)的一种成熟方法。由于研究对象、方法和疗效评估指标的差异,文献报道的手术疗效存在很大差异。
目的
比较关节镜下清创术与保守治疗对Kellgren-Lawrence Ⅰ-Ⅲ级KOA的中期疗效。
方法
选取2018年7月至2018年12月我院骨科门诊收治的Kellgren-Lawrence Ⅰ-Ⅲ级KOA患者,同意接受关节镜手术的纳入关节镜下清创组,拒绝手术治疗的纳入保守治疗组。记录性别、年龄、体重指数(BMI)、KOA患侧、治疗前美国特种外科医院膝关节评分(HSS评分)、治疗前行走及休息时视觉模拟评分(VAS评分)、保守治疗内容及手术过程。两组患者在治疗后1、3、6、12和24个月进行门诊随访。对每组治疗前后HSS评分和VAS评分的变化进行统计学分析,并比较两组在不同治疗阶段HSS评分和VAS评分的差异。
结果
保守治疗组有80例患者获得完整随访资料,其中男性20例,女性60例,年龄58.75±14.66岁。膝关节镜下清创组有98例患者获得完整随访资料,其中男性24例,女性74例,年龄59.27±14.48岁。两组治疗前一般资料(性别、年龄、BMI、KOA患侧、Kellgren-Lawrence分级分布、HSS评分和VAS评分)比较,差异无统计学意义。保守治疗组治疗后1、3、6、12和24个月的HSS评分均显著高于治疗前(P<0.05)。保守治疗组在1、3、6、12和24个月的HSS评分比较,差异无统计学意义(P>0.05)。膝关节镜下清创组术后1个月的HSS评分显著高于术前(P<0.05)。膝关节镜下清创组术后3、6、12和24个月的HSS评分均显著高于术前及术后1个月(P<0.05)。术后3、6、12和24个月的HSS评分比较,差异无统计学意义(P>0.05)。术后3、6、12和24个月,关节镜下清创组的HSS评分显著高于保守治疗组(P<0.05)。两组治疗前及随访1个月时的HSS评分比较,差异无统计学意义(P>0.05)。两组行走及休息时的VAS评分均显著降低,且关节镜下清创组休息时的VAS评分显著低于保守治疗组,但治疗后两组行走时的VAS评分差异无统计学意义。
结论
与保守治疗相比,关节镜下清创术可在治疗后2年内显著改善Kellgren-Lawrence Ⅰ-Ⅲ级KOA患者的膝关节静息痛和膝关节功能状态。