4岁抗N-甲基-D-天冬氨酸受体脑炎合并卵巢畸胎瘤患者：病例报告
Four-year-old anti-N-methyl-D-aspartate receptor encephalitis patient with ovarian teratoma: A case report.
作者信息
Xue Cong-Ying, Dong Hui, Yang Hui-Xia, Jiang Yu-Wu, Yin Ling
机构信息
Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing 100034, China.
Department of Pediatrics, Peking University First Hospital, Beijing 100034, China.
出版信息
World J Clin Cases. 2021 Jul 6;9(19):5319-5324. doi: 10.12998/wjcc.v9.i19.5319.
BACKGROUND
A population-based comparative study in United States shows that the prevalence and incidence of autoimmune encephalitis are comparable to those of infectious encephalitis and its detection is increasing over time. Some patients are complicated with ovarian teratoma. The younger the patient is, the less likely a tumor will be present.
CASE SUMMARY
This case report describes the successful treatment of anti-N-methyl-D-aspartate-receptor (NMDAR) encephalitis by early laparoscopic ovarian cystectomy and immunotherapy in a 4-year-old female child. And to the best of our knowledge, this detailed case report describes the youngest patient to date with anti-NMDAR encephalitis who underwent laparoscopic ovarian cystectomy.
CONCLUSION
Although the younger the patient is, the less likely a tumor will be detected, we still emphasize that all patients with suspected or confirmed anti-NMDAR encephalitis should be screened for ovarian tumors if possible. Prompt initiation of immunotherapy and tumor removal are crucial for good outcomes.
背景
美国一项基于人群的比较研究表明，自身免疫性脑炎的患病率和发病率与感染性脑炎相当，且其检出率随时间推移不断增加。部分患者合并卵巢畸胎瘤。患者年龄越小，肿瘤存在的可能性越小。
病例摘要
本病例报告描述了一名4岁女童通过早期腹腔镜卵巢囊肿切除术和免疫疗法成功治疗抗N-甲基-D-天冬氨酸受体（NMDAR）脑炎的过程。据我们所知，这份详细的病例报告描述了迄今为止接受腹腔镜卵巢囊肿切除术的最年轻的抗NMDAR脑炎患者。
结论
尽管患者年龄越小，检测到肿瘤的可能性越小，但我们仍强调，所有疑似或确诊抗NMDAR脑炎的患者都应尽可能筛查卵巢肿瘤。及时开始免疫治疗和切除肿瘤对取得良好疗效至关重要。
Zotero 插件