Hong Xu-Lin, Chen Hao, Li Ya, Teeroovengadum Hema Darinee, Fu Guo-Sheng, Zhang Wen-Bin
Department of Cardiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang Province, China.
World J Clin Cases. 2021 Jul 16;9(20):5453-5461. doi: 10.12998/wjcc.v9.i20.5453.
Coronary artery disease (CAD) is one of the leading causes of death and disease burden in China and worldwide. A practical and reliable prediction scoring system for CAD risk and severity evaluation is urgently needed for primary prevention.
To examine whether the prediction for atherosclerotic cardiovascular disease risk in China (China-PAR) scoring system could be used for this purpose.
A total of 6813 consecutive patients who underwent diagnostic coronary angiography were enrolled. The China-PAR score was calculated for each patient and CAD severity was assessed by the Gensini score (GS).
Correlation analysis demonstrated a significant relationship between China-PAR and GS ( = 0.266, < 0.001). In receiver operating characteristic curve analysis, the cut-off values of China-PAR for predicting the presence and the severity of CAD were 7.55% with a sensitivity of 55.8% and specificity of 71.8% [area under the curve (AUC) = 0.693, 95% confidence interval: 0.681 to 0.706, < 0.001], and 7.45% with a sensitivity of 58.8% and specificity of 67.2% (AUC = 0.680, 95% confidence interval: 0.665 to 0.694, < 0.001), respectively.
The China-PAR scoring system may be useful in predicting the presence and severity of CAD.
冠状动脉疾病（CAD）是中国乃至全球死亡和疾病负担的主要原因之一。基层医疗预防迫切需要一个实用且可靠的用于评估CAD风险和严重程度的预测评分系统。
检验中国动脉粥样硬化性心血管疾病风险评估（China-PAR）评分系统是否可用于此目的。
连续纳入6813例行诊断性冠状动脉造影的患者。计算每位患者的China-PAR评分，并采用Gensini评分（GS）评估CAD严重程度。
相关性分析显示China-PAR与GS之间存在显著相关性（ = 0.266， < 0.001）。在受试者工作特征曲线分析中，China-PAR预测CAD存在和严重程度的截断值分别为7.55%，灵敏度为55.8%，特异度为71.8% [曲线下面积（AUC） = 0.693，95%置信区间：0.681至0.706， < 0.001]，以及7.45%，灵敏度为58.8%，特异度为67.2%（AUC = 0.680，95%置信区间：0.665至0.694， < 0.001）。
China-PAR评分系统可能有助于预测CAD的存在和严重程度。
