缺血性脑增生性血管病的出血性转化：一例报告。
Hemorrhagic transformation of ischemic cerebral proliferative angiopathy: A case report.
作者信息
Xia Yu, Yu Xian-Feng, Ma Zhen-Juan, Sun Zhong-Wu
机构信息
Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China.
出版信息
World J Clin Cases. 2021 Jul 16;9(20):5730-5736. doi: 10.12998/wjcc.v9.i20.5730.
BACKGROUND
Cerebral proliferative angiopathy (CPA) is a rare vascular disease characterized by the presence of diffuse vascular proliferation, progressive vascular hyperflow and vasodilation of multiple vessels in the normal brain parenchyma. Unlike cerebral arteriovenous malformations, CPA has a mixed appearance between that of lesions with cell proliferation and endothelial proliferation. To date, the pathogenesis of CPA is unclear, in which changes induced by cortical ischemia in the elastic layer of the blood supply artery and smooth muscle cells may be involved.
CASE SUMMARY
In this article, we retrospectively analyzed a case of hemorrhagic transformation of ischemic CPA diagnosed by digital subtraction angiography and reviewed the related literature for further exploration of its pathogenesis, diagnosis and treatment.
CONCLUSION
The information in the present case report may facilitate further clinical research on this cerebrovascular disease.
背景
脑增殖性血管病（CPA）是一种罕见的血管疾病，其特征是在正常脑实质中存在弥漫性血管增殖、进行性血管高流量以及多支血管的血管扩张。与脑动静脉畸形不同，CPA在细胞增殖和内皮细胞增殖的病变之间呈现混合外观。迄今为止，CPA的发病机制尚不清楚，可能涉及供血动脉弹性层和平滑肌细胞中皮质缺血所诱导的变化。
病例摘要
在本文中，我们回顾性分析了一例经数字减影血管造影诊断为缺血性CPA出血转化的病例，并复习相关文献以进一步探讨其发病机制、诊断和治疗。
结论
本病例报告中的信息可能有助于对这种脑血管疾病的进一步临床研究。
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