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维生素E和维生素A对大肠杆菌感染鸡的体液免疫和吞噬作用的影响。

Effect of vitamin E and A on humoral immunity and phagocytosis in E. coli infected chicken.

作者信息

Tengerdy R P, Brown J C

出版信息

Poult Sci. 1977 May;56(3):957-63. doi: 10.3382/ps.0560957.

DOI:10.3382/ps.0560957
PMID:343085
Abstract

Dietary supplementation of either vitamin E (300 mg./kg. diet) or vitamin A (60,000 I.U./kg. diet) significantly reduced E. coli caused mortality, but the combination of the two vitamins did not. Protection was attributed to increased antibody production and increased phagocytosis, although neither factor alone gave a significant correlation with mortality. Vitamin E level significantly increased especially in the spleen of supplemented chicks, but vitamin A suppressed this increase, partially explaining the lack of protection in vitamin E and A supplemented chicks.

摘要

在日粮中添加维生素E(300毫克/千克日粮)或维生素A(60,000国际单位/千克日粮)均可显著降低大肠杆菌引起的死亡率,但两种维生素联合使用时却无此效果。保护作用归因于抗体产生增加和吞噬作用增强,尽管单独这两个因素与死亡率均无显著相关性。补充维生素E组雏鸡的维生素E水平显著升高,尤其是在脾脏中,但维生素A抑制了这种升高,这部分解释了同时补充维生素E和A的雏鸡缺乏保护作用的原因。

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