Taiwo Adewale Matthew, Olukayode Stephen, Ojekunle Oluwaseyi Zacchaeus, Oyedepo John Adebayo, Awomeso Julius Awonusi, Gbadebo Adewole Michael
Department of Environmental Management and Toxicology, Federal University of Agriculture, PMB 2240, Abeokuta, Ogun State, Nigeria.
Institute of Food Security, Environmental Resources and Agricultural Research (IFSERAR), Federal University of Agriculture, PMB 2240, Abeokuta, Ogun State, Nigeria.
Biol Trace Elem Res. 2022 May;200(5):2519-2527. doi: 10.1007/s12011-021-02839-3. Epub 2021 Jul 26.
The monitoring of food contamination by trace elemental impurities (TEIs) are major health challenges in developing countries. The present study evaluated the content and toxicological risk assessment of TEIs in commonly consumed snack/junk foods from Ogun State, Nigeria. TEIs (Pb and Cr) were determined in sixty snack food samples purchased from Ijebu Ode, Ogun State, southwestern Nigeria. The TEIs were analysed in quadruplicates using atomic absorption spectrometry with flame atomization. TEI data were subjected to simple descriptive and inferential statistics. The toxicological risk assessment of TEIs was evaluated for hazard quotient (HQ), hazard index (HI) and cancer risk (CR) using the United States Environmental Protection Agency-Integrated Risk Information System (USEPA-IRIS) model. Data showed the varying Pb levels of 8.22 ± 1.57 mg/kg in sausage to 12.25 ± 4.27 mg/kg in cocoyam chips higher than the permissible limit of the Codex Alimentarius of the Joint World Health Organization and Food and Agriculture Organization. The toxicological risk assessment revealed the HQs greater than 1.0 for Pb and Cr in most snack foods consumed by adults and children, indicating adverse health problems. The CRs of Pb (children) and Cr (adults and children) also breached the acceptable limit of 1.0 × 10, signifying possible lifetime development of cancer. It is therefore necessary to periodically monitor the TEIs in snacks to protect the public health.
监测痕量元素杂质(TEIs)对食品的污染是发展中国家面临的重大健康挑战。本研究评估了尼日利亚奥贡州常见的休闲/垃圾食品中TEIs的含量及毒理学风险评估。从尼日利亚西南部奥贡州伊杰布奥德购买的60份休闲食品样本中测定了TEIs(铅和铬)。使用火焰原子化的原子吸收光谱法对TEIs进行了四次重复分析。TEI数据进行了简单的描述性和推断性统计。使用美国环境保护局综合风险信息系统(USEPA-IRIS)模型,对TEIs的毒理学风险评估进行了危害商数(HQ)、危害指数(HI)和癌症风险(CR)的评估。数据显示,香肠中铅含量为8.22±1.57毫克/千克,木薯片中铅含量为12.25±4.27毫克/千克,高于世界卫生组织和粮食及农业组织食品法典的允许限量。毒理学风险评估显示,大多数成人和儿童食用的休闲食品中铅和铬的HQ大于1.0,表明存在不良健康问题。儿童铅的CR和成人及儿童铬的CR也突破了可接受的1.0×10的限值,意味着可能终生患癌。因此,有必要定期监测休闲食品中的TEIs,以保护公众健康。