Department of Veterinary Public Health and Preventive Medicine, University of Ibadan, Nigeria.
Department of Veterinary Pathology, University of Ibadan, Nigeria.
Vet Ital. 2021 Jun 28;57(1):71-77. doi: 10.12834/VetIt.1787.9429.2.
This study was conducted to profile the antibody levels to rabies in dogs presented at veterinary clinics and determine rabies awareness among dog owners in Abeokuta, Nigeria. Records of dogs' rabies vaccination were obtained to determine their vaccination status and number of times they had been vaccinated. Sera from 138 dogs of consenting owners were analysed using indirect ELISA technique to detect rabies antibodies. Structured questionnaire was administered to 138 dog owners to determine their awareness on rabies. Data were analysed using descriptive statistics, Chi‑square, ANOVA and t‑test at p ≤ 0.05. Of 138 dogs screened, 114 (82.6%) had history of vaccination against rabies. Of these 114, 87 (76.3%) were seronegative; however, 5 (3.6%) of the 24 unvaccinated dogs were seropositive. Overall, 32 (23.2%) comprising 15 (10.8%) males and 17 (12.3%) females had positive rabies antibodies level. Five (3.6%), 3 (12.1%) and 24 (17.4%) were seropositive among dogs of < 6 months, 6‑12 months and > 1 year of age, respectively. Dogs > 1 year had significantly higher antibodies than < 6 months (p < 0.05). Most (86.9%) of the dog owners were aware of rabies. The low seroconversion in vaccinated dogs and prevalence of rabies antibodies in unvaccinated dogs are of public health concern. There is need for regular sero‑profiling of vaccinated and unvaccinated dogs.
本研究旨在分析就诊于兽医诊所的犬只的狂犬病抗体水平,并确定尼日利亚阿贝奥库塔的犬主对狂犬病的认识。获取了犬只狂犬病疫苗接种记录,以确定其接种状态和接种次数。使用间接 ELISA 技术分析了 138 只同意主人的血清,以检测狂犬病抗体。向 138 名犬主发放了结构化问卷,以确定他们对狂犬病的认识。使用描述性统计、卡方检验、方差分析和 t 检验进行数据分析,p≤0.05。在筛查的 138 只犬中,114 只(82.6%)有狂犬病疫苗接种史。在这些 114 只中,87 只(76.3%)为血清阴性;然而,24 只未接种疫苗的犬中有 5 只为血清阳性。总体而言,32 只(23.2%)犬的狂犬病抗体水平呈阳性,其中 15 只为雄性(10.8%),17 只为雌性(12.3%)。在<6 个月、6-12 个月和>1 岁的犬中,分别有 5 只(3.6%)、3 只(12.1%)和 24 只(17.4%)为血清阳性。>1 岁的犬的抗体水平明显高于<6 个月的犬(p<0.05)。大多数(86.9%)犬主都知道狂犬病。接种疫苗的犬只血清转化率低和未接种疫苗的犬只狂犬病抗体流行率令人关注。需要定期对接种疫苗和未接种疫苗的犬只进行血清学分析。