Specialist Centre for Kidney Cancer, Royal Free London NHS Foundation Trust, Hampstead, London, UK.
Department of Urology, Cabueñes University Hospital, Gijón, Spain.
J Robot Surg. 2022 Jun;16(3):611-619. doi: 10.1007/s11701-021-01285-6. Epub 2021 Jul 27.
To assess the impact of body mass index (BMI) on peri-operative outcomes of kidney and upper tract robot-assisted surgery. Medical audit of patients who underwent robot-assisted kidney and upper tract cancer surgery at a single institution between 2017 and 2019, categorized on BMI into obese patients with a BMI ≥ 30 kg/m and a control group with BMI < 25 kg/m. Patient and tumour characteristics, surgery time, intraoperative blood loss, intraoperative adverse events (AE) according to the European Association of Urology Intraoperative Adverse Incidents Classification (EAUiaiC), conversion- to-open/radical rate as well as 30-day postoperative AE according to Clavien-Dindo (CD) and length of inpatient stay were analyzed. 366 patients were identified, 141 with a BMI < 25 (normal-weight) and 225 BMI ≥ 30 (obesity). There were no significant differences between the groups in terms of age, gender, comorbidities, tumour size, TNM stage and type of surgery. Obese patients had a higher estimated blood loss (198.05 ml), surgery time (171.75 min), intraoperative AE (all grades) (14.67%, 95% CI (0.10-0.19) as well as adherent perinephric fat (APF) (14.22%, 95% CI (0.09-0.19)) in contrast to the control group (86.85 ml, 148.29 min, 7.04% and 2.12%, respectively). Hospital stay, major intraoperative AE (≥ 3) and major postoperative AE (CD > 2) distributed equally between groups. Robotic kidney and upper tract surgery in obese patients showed an increase in surgery time and blood loss potentially related to APF. However, obesity was not associated with conversion to open surgery or radical nephrectomy in nephron-sparing procedures, length of stay, major intraoperative AE or postoperative complications.
评估体重指数 (BMI) 对肾脏和上尿路机器人辅助手术围手术期结果的影响。对 2017 年至 2019 年间在一家机构接受机器人辅助肾脏和上尿路癌症手术的患者进行医学审核,根据 BMI 将患者分为肥胖患者(BMI≥30kg/m)和对照组(BMI<25kg/m)。分析患者和肿瘤特征、手术时间、术中出血量、根据欧洲泌尿外科学会术中不良事件分类 (EAUiaiC) 分类的术中不良事件 (AE)、中转开放/根治率以及根据 Clavien-Dindo (CD) 分类的 30 天术后 AE 和住院时间。共确定 366 例患者,其中 141 例 BMI<25(正常体重),225 例 BMI≥30(肥胖)。两组在年龄、性别、合并症、肿瘤大小、TNM 分期和手术类型方面无显著差异。肥胖患者的估计出血量(198.05ml)、手术时间(171.75min)、术中 AE(所有等级)(14.67%,95%CI(0.10-0.19))和附着肾周脂肪(APF)(14.22%,95%CI(0.09-0.19))均高于对照组(86.85ml、148.29min、7.04%和 2.12%)。住院时间、严重术中 AE(≥3)和严重术后 AE(CD>2)在两组间分布均等。肥胖患者的机器人肾脏和上尿路手术显示手术时间和出血量增加,可能与 APF 有关。然而,肥胖与保肾手术中转开放手术或根治性肾切除术、住院时间、严重术中 AE 或术后并发症无关。