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喉镜下特征与声带白斑癌变风险的关系。

Laryngoscopic characteristics related to the risk of cancerization of vocal cord leukoplakia.

机构信息

Department of Otorhinolaryngology, The People's Hospital of Wenshan Prefecture, Yunnan, China.

Department of Otolaryngology Head and Neck Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

出版信息

Acta Otolaryngol. 2021 Aug;141(8):802-807. doi: 10.1080/00016489.2021.1951444. Epub 2021 Jul 27.

DOI:10.1080/00016489.2021.1951444
PMID:34314296
Abstract

BACKGROUND

The diagnosis of vocal cord leukoplakia mainly relies on laryngoscopy. The morphology of vocal cord leukoplakia under laryngoscope is closely related to the pathological nature of leukoplakia. The specific manifestations associated with high-risk vocal cord leukoplakia remain to be explored.

OBJECTIVE

To investigate the characteristics of low-risk and high-risk vocal cord leukoplakia under conventional white light imaging (WLI) laryngoscopy and its correlations with narrow band imaging (NBI) laryngoscopy.

METHODS

One hundred and seventy-five cases of vocal cord leukoplakia were divided into low-risk and high-risk groups. The characteristics of low-risk and high-risk vocal cord leukoplakia under WLI laryngoscopy and its correlations with NBI laryngoscopy were analyzed.

RESULTS

Logistic regression analysis showed that thickness and hyperemia were independent factors ( < .05). Hyperemia had a strong consistency with the visualization of spots under NBI laryngoscopy (kappa = 0.758). The sign of hyperemia and the NBI classification had equivalent diagnostic efficacy for predicting the risk of cancerization of vocal cord leukoplakia.

CONCLUSION

The sign of hyperemia under WLI laryngoscopy is significantly correlated with the visualized spots under NBI laryngoscopy. Hyperemia is an important feature for predicting malignant potential of vocal cord leukoplakia.

摘要

背景

声带白斑的诊断主要依赖于喉镜检查。喉镜下声带白斑的形态与白斑的病理性质密切相关,与声带白斑高风险相关的具体表现仍有待探索。

目的

探讨常规白光成像(WLI)喉镜下低风险和高风险声带白斑的特征及其与窄带成像(NBI)喉镜的相关性。

方法

将 175 例声带白斑病例分为低风险组和高风险组。分析 WLI 喉镜下低风险和高风险声带白斑的特征及其与 NBI 喉镜的相关性。

结果

Logistic 回归分析显示,厚度和充血是独立的影响因素( < .05)。充血与 NBI 喉镜下斑点的可视化具有很强的一致性(kappa = 0.758)。充血征象和 NBI 分类对预测声带白斑癌变风险具有同等的诊断效果。

结论

WLI 喉镜下的充血征象与 NBI 喉镜下的可视化斑点显著相关。充血是预测声带白斑恶性潜能的重要特征。

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引用本文的文献

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[Application of electronic laryngoscope combined with narrow band imaging endoscope and its classification in the diagnosis of vocal cord leukoplakia].电子喉镜联合窄带成像内镜在声带白斑诊断中的应用及其分类
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Nov;38(11):1006-1011. doi: 10.13201/j.issn.2096-7993.2024.11.003.
2
Comparing suspension laryngoscopic mucosal dissection and plasma resection for laryngeal leukoplakia: prognostic outcomes.比较支撑喉镜下黏膜切除术与等离子切除术治疗喉白斑病的预后结果
Am J Transl Res. 2024 Feb 15;16(2):515-523. doi: 10.62347/NXGS1826. eCollection 2024.
3
The sensitivity of laryngeal findings in predicting high-grade dysplasia in patients with vocal fold leukoplakia undergoing office-based biopsies: A retrospective analysis of 100 cases.
在接受门诊活检的声带白斑患者中,喉部检查结果对预测高级别发育异常的敏感性:100例病例的回顾性分析
Laryngoscope Investig Otolaryngol. 2024 Jan 4;9(1):e1209. doi: 10.1002/lio2.1209. eCollection 2024 Feb.